SCOPe 2.06: Domain d4or5a_: 4or5 A:

Lineage for d4or5a_ (4or5 A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.7: Protein kinases, catalytic subunit [88854] (66 proteins)
   members organized in the groups and subfamiles specified by the comments

6. Protein automated matches [190091] (17 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188447] (653 PDB entries)

8. Domain d4or5a_: 4or5 A: [263334]
   Other proteins in same PDB: d4or5b1, d4or5b2, d4or5g1, d4or5g2
   automated match to d3miaa_
   protein/RNA complex; complexed with so4, yt3, zn

Details for d4or5a_

PDB Entry: 4or5, 2.9 Å

PDB Description: Crystal structure of HIV-1 Tat complexed with human P-TEFb and AFF4

PDB Compounds: (A:) Cyclin-dependent kinase 9

SCOPe Domain Sequences for d4or5a_:

Sequence, based on SEQRES records:

>d4or5a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkaspynrckgsiylvfdfcehdlagllsnvlvkftlseik
rvmqmllnglyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytn
rvvtlwyrppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgs
itpevwpnvdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsd
dalnhdffwsdpmpsdlkgmlsth

Sequence, based on observed residues (ATOM records):

>d4or5a_ d.144.1.7 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vecpfcdevskyeklakigqgtfgevfkarhrktgqkvalkkvlmenekegfpitalrei
kilqllkhenvvnlieicrtkaspkgsiylvfdfcehdlagllsnvlvkftlseikrvmq
mllnglyyihrnkilhrdmkaanvlitrdgvlkladfglarafslaknsqpnrytnrvvt
lwyrppelllgerdygppidlwgagcimaemwtrspimqgnteqhqlalisqlcgsitpe
vwpnvdnyelyeklelvkgqkrkvkdrlkayvrdpyaldlidkllvldpaqridsddaln
hdffwsdpmpsdlkgmlsth

Timeline for d4or5a_:

• d4or5a_ first appeared in SCOPe 2.05
  
• d4or5a_ appears in SCOPe 2.07
  
• d4or5a_ appears in the current release, SCOPe 2.08