SCOPe 2.06: Domain d4o1lb_: 4o1l B:

Lineage for d4o1lb_ (4o1l B:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.72: Ribokinase-like [53612] (3 superfamilies)
   core: 3 layers: a/b/a; mixed beta-sheet of 8 strands, order 21345678, strand 7 is antiparallel to the rest
   potential superfamily: members of this fold have similar functions but different ATP-binding sites

4. Superfamily c.72.1: Ribokinase-like [53613] (6 families)
   has extra strand located between strands 2 and 3

5. Family c.72.1.1: Ribokinase-like [53614] (10 proteins)
   automatically mapped to Pfam PF00294

6. Protein Adenosine kinase [53617] (3 species)

7. Species Human (Homo sapiens) [TaxId:9606] [53618] (4 PDB entries)

8. Domain d4o1lb_: 4o1l B: [263244]
   automated match to d2i6aa_
   complexed with ho4, mg

Details for d4o1lb_

PDB Entry: 4o1l, 2.5 Å

PDB Description: Human Adenosine Kinase in complex with inhibitor

PDB Compounds: (B:) adenosine kinase

SCOPe Domain Sequences for d4o1lb_:

Sequence, based on SEQRES records:

>d4o1lb_ c.72.1.1 (B:) Adenosine kinase {Human (Homo sapiens) [TaxId: 9606]}
apqalrenilfgmgnplldisavvdkdfldkyslkpndqilaedkhkelfdelvkkfkve
yhaggstqnsikvaqwmiqqphkaatffgcigidkfgeilkrkaaeahvdahyyeqneqp
tgtcaacitgdnrslianlaaancykkekhldleknwmlvekarvcyiagffltvspesv
lkvahhasennriftlnlsapfisqfykeslmkvmpyvdilfgneteaatfareqgfetk
dikeiakktqalpkmnskrqriviftqgrddtimatesevtafavldqdqkeiidtngag
dafvggflsqlvsdkplteciraghyaasiiirrtgctfpekpdfh

Sequence, based on observed residues (ATOM records):

>d4o1lb_ c.72.1.1 (B:) Adenosine kinase {Human (Homo sapiens) [TaxId: 9606]}
apqalrenilfgmgnplldisavvdkdfldkyslkpndqilaedkhkelfdelvkkfkve
yhaggstqnsikvaqwmiqqphkaatffgcigidkfgeilkrkaaeahvdahyyeqneqp
tgtcaacitgdnrslianlaaancykkekhldleknwmlvekarvcyiagffltvspesv
lkvahhasennriftlnlsapfisqfykeslmkvmpyvdilfgneteaatfareqgfetk
dikeiakktqalpkmnskrqriviftqgrddtimatesevtafavlidtngagdafvggf
lsqlvsdkplteciraghyaasiiirrtgctfpekpdfh

Timeline for d4o1lb_:

• d4o1lb_ first appeared in SCOPe 2.05
  
• d4o1lb_ appears in SCOPe 2.07
  
• d4o1lb_ appears in the current release, SCOPe 2.08