SCOPe 2.08: Domain d4nyfa_: 4nyf A:

Lineage for d4nyfa_ (4nyf A:)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.55: Ribonuclease H-like motif [53066] (7 superfamilies)
   3 layers: a/b/a; mixed beta-sheet of 5 strands, order 32145; strand 2 is antiparallel to the rest

4. Superfamily c.55.3: Ribonuclease H-like [53098] (18 families)
   consists of one domain of this fold

5. Family c.55.3.2: Retroviral integrase, catalytic domain [53107] (2 proteins)
   Pfam PF00665

6. Protein Retroviral integrase, catalytic domain [53108] (5 species)

7. Species Human immunodeficiency virus type 1 [TaxId:11676] [53110] (74 PDB entries)

8. Domain d4nyfa_: 4nyf A: [263234]
   automated match to d3vq9c_
   complexed with 4bi, cd

Details for d4nyfa_

PDB Entry: 4nyf, 1.9 Å

PDB Description: HIV integrase in complex with inhibitor

PDB Compounds: (A:) integrase

SCOPe Domain Sequences for d4nyfa_:

Sequence, based on SEQRES records:

>d4nyfa_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktiht
dngsnftsatvkaacdwagikqedgipynpqsqgvvesmnkelkkiigqvrdqaehlkta
vqmavfihnkkrkggiggysagerivdiiatdiqt

Sequence, based on observed residues (ATOM records):

>d4nyfa_ c.55.3.2 (A:) Retroviral integrase, catalytic domain {Human immunodeficiency virus type 1 [TaxId: 11676]}
sspgiwqldcthlegkvilvavhvasgyieaevipaetgqetayfllklagrwpvktiht
dngsnftsatvkaacdwagikqepqsqgvvesmnkelkkiigqvrdqaehlktavqmavf
ihnkkrkggiggysagerivdiiatdiqt

Timeline for d4nyfa_:

• d4nyfa_ first appeared in SCOPe 2.05
  
• d4nyfa_ appears in SCOPe 2.07