SCOPe 2.07: Domain d4nsta_: 4nst A:

Lineage for d4nsta_ (4nst A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d4nsta_: 4nst A: [263220]
   Other proteins in same PDB: d4nstb1, d4nstb2, d4nstd1, d4nstd2
   automated match to d4un0c_
   protein/RNA complex; complexed with adp, af3, edo, mg

Details for d4nsta_

PDB Entry: 4nst, 2.2 Å

PDB Description: Crystal structure of human Cdk12/Cyclin K in complex with ADP-aluminum fluoride

PDB Compounds: (A:) cyclin-dependent kinase 12

SCOPe Domain Sequences for d4nsta_:

Sequence, based on SEQRES records:

>d4nsta_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
esdwgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitairei
kilrqlihrsvvnmkeivtdkqdaldfkkdkgafylvfeymdhdlmgllesglvhfsedh
iksfmkqlmegleychkknflhrdikcsnillnnsgqikladfglarlynseesrpytnk
vitlwyrppelllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgsp
cpavwpdviklpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtl
qsdflkdvelskmappdlphwqdchelwskk

Sequence, based on observed residues (ATOM records):

>d4nsta_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
esdwgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitairei
kilrqlihrsvvnmkeivtdkqdgafylvfeymdhdlmgllesglvhfsedhiksfmkql
megleychkknflhrdikcsnillnnsgqikladfglarlynseesrpytnkvitlwyrp
pelllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcpavwpdv
iklpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqsdflkdv
elskmappdlphwqdchelwskk

Timeline for d4nsta_:

• d4nsta_ first appeared in SCOPe 2.05
  
• d4nsta_ appears in SCOPe 2.06
  
• d4nsta_ appears in the current release, SCOPe 2.08