SCOPe 2.08: Domain d4leme1: 4lem E:1-542

Lineage for d4leme1 (4lem E:1-542)

1. Root: SCOPe 2.08

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (61 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [225379] (7 PDB entries)

8. Domain d4leme1: 4lem E:1-542 [262935]
   Other proteins in same PDB: d4lema2, d4lemb2, d4lemc2, d4lemd2, d4leme2
   automated match to d4e3xb_
   complexed with b12, mg

Details for d4leme1

PDB Entry: 4lem, 2.27 Å

PDB Description: crystal structure of the delta-pyrroline-5-carboxylate dehydrogenase from mycobacterium tuberculosis

PDB Compounds: (E:) 1-pyrroline-5-carboxylate dehydrogenase

SCOPe Domain Sequences for d4leme1:

Sequence, based on SEQRES records:

>d4leme1 c.82.1.0 (E:1-542) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
mdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgeridv
vqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwre
kiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpld
gfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvinl
vtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdfv
vahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdit
dlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddptde
sfvieyfgpllsvhvypderyeqildvidtgsryaltgaviaddrqavltaldrlrfaag
nfyvndkptgavvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyphm
av

Sequence, based on observed residues (ATOM records):

>d4leme1 c.82.1.0 (E:1-542) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
mdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgeridv
vqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwre
kiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpld
gfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvinl
vtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdfv
vahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdit
dlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddptde
sfvieyfgpllsvhvypderyeqildvidtgyaltgaviaddrqavltaldrlrfaagnf
yvndkptavvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyphmav

Timeline for d4leme1:

• d4leme1 first appeared in SCOPe 2.05, called d4leme_
  
• d4leme1 appears in SCOPe 2.07