SCOPe 2.05: Domain d4lemb_: 4lem B:

Lineage for d4lemb_ (4lem B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.82: ALDH-like [53719] (1 superfamily)
   consists of two similar domains with 3 layers (a/b/a) each; duplication
   core: parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.82.1: ALDH-like [53720] (3 families)
   binds NAD differently from other NAD(P)-dependent oxidoreductases

5. Family c.82.1.0: automated matches [191448] (1 protein)
   not a true family

6. Protein automated matches [190683] (38 species)
   not a true protein

7. Species Mycobacterium tuberculosis [TaxId:83332] [225379] (7 PDB entries)

8. Domain d4lemb_: 4lem B: [262932]
   automated match to d4e3xb_
   complexed with b12, mg

Details for d4lemb_

PDB Entry: 4lem, 2.27 Å

PDB Description: crystal structure of the delta-pyrroline-5-carboxylate dehydrogenase from mycobacterium tuberculosis

PDB Compounds: (B:) 1-pyrroline-5-carboxylate dehydrogenase

SCOPe Domain Sequences for d4lemb_:

Sequence; same for both SEQRES and ATOM records:

>d4lemb_ c.82.1.0 (B:) automated matches {Mycobacterium tuberculosis [TaxId: 83332]}
hmdaitqvpvpanepvhdyapkspertrlrtelasladhpidlphviggrhrmgdgerid
vvqphrhaarlgtltnathadaaaaveaamsaksdwaalpfderaavflraadllagpwr
ekiaaatmlgqsksvyqaeidavcelidfwrfnvafarqileqqpisgpgewnridyrpl
dgfvyaitpfnftsiagnlptapalmgntviwkpsitqtlaayltmqlleaaglppgvin
lvtgdgfavsdvaladprlagihftgstatfghlwqwvgtnigryhsyprlvgetggkdf
vvahasarpdvlrtalirgafdyqgqkcsavsrafiahsvwqrmgdellakaaelrygdi
tdlsnyggalidqrafvknvdaierakgaaavtvavggeyddsegyfvrptvllsddptd
esfvieyfgpllsvhvypderyeqildvidtgsryaltgaviaddrqavltaldrlrfaa
gnfyvndkptgavvgrqpfggargsdtndkagsplnllrwtsarsiketfvaatdhiyph
mav

Timeline for d4lemb_:

• d4lemb_ is new in SCOPe 2.05-stable
  
• d4lemb_ is called d4lemb1 in SCOPe 2.06
  
• d4lemb_ appears in the current release, SCOPe 2.08, called d4lemb1