SCOPe 2.05: Domain d4ffxd_: 4ffx D:

Lineage for d4ffxd_ (4ffx D:)

1. Root: SCOPe 2.05

2. Class a: All alpha proteins [46456] (286 folds)

3. Fold a.127: L-aspartase-like [48556] (1 superfamily)
   multihelical, consists of three all-alpha domains

4. Superfamily a.127.1: L-aspartase-like [48557] (3 families)

5. Family a.127.1.0: automated matches [191431] (1 protein)
   not a true family

6. Protein automated matches [190621] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [256256] (4 PDB entries)

8. Domain d4ffxd_: 4ffx D: [262705]
   automated match to d4ffxc_
   mutant

Details for d4ffxd_

PDB Entry: 4ffx, 2.7 Å

PDB Description: structural and biochemical characterization of human adenylosuccinate lyase (adsl) and the r303c adsl deficiency associated mutation

PDB Compounds: (D:) adenylosuccinate lyase

SCOPe Domain Sequences for d4ffxd_:

Sequence, based on SEQRES records:

>d4ffxd_ a.127.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gdhgspdsyrsplasryaspemcfvfsdrykfrtwrqlwlwlaeaeqtlglpitdeqire
mksnlenidfkmaaeeekrlrhdvmahvhtfghccpkaagiihlgatscyvgdntdliil
rnaldlllpklarvisrladfakeraslptlgfthfqpaqlttvgkrcclwiqdlcmdlq
nlkrvrddlrfrgvkgttgtqasflqlfegddhkveqldkmvtekagfkrafiitgqtyt
rkvdievlsvlaslgasvhkictdirllanlkemeepfekqqigssampykrnpmrserc
cslarhlmtlvmdplqtasvqwfertlddsanrriclaeafltadtilntlqniseglvv
ypkvierrirqelpfmateniimamvkaggsrqdchekirvlsqqaasvvkqeggdndli
eriqvdayfspihsqldhlldpssftgrasqqvqrfleeevypllkpye

Sequence, based on observed residues (ATOM records):

>d4ffxd_ a.127.1.0 (D:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gdhgspdsyrsplasryaspemcfvfsdrykfrtwrqlwlwlaeaeqtlglpitdiremk
snlenidfkmaaeeekrldvmahvhtfghccpkaagiihlgatscyvgdntdliilrnal
dlllpklarvisrladfakeraslptlgfthfqpaqlttvgkrcclwiqdlcmdlqnlkr
vrddlrfrgvkgttgtqasflqlfegddhkveqldkmvtekagfkrafiitgqtytrkvd
ievlsvlaslgasvhkictdirllanlkemeepfepykrnpmrserccslarhlmtlvmd
plqtasvqwfertlddsanrriclaeafltadtilntlqniseglvvypkvierrirqel
pfmateniimamvkaggsrqdchekirvlsqqaasvvkqeggdndlieriqvdayfspih
sqldhlldpssftgrasqqvqrfleeevypllkpye

Timeline for d4ffxd_:

• d4ffxd_ is new in SCOPe 2.05-stable
  
• d4ffxd_ appears in SCOPe 2.06
  
• d4ffxd_ appears in the current release, SCOPe 2.08