SCOPe 2.06: Domain d4cxaa_: 4cxa A:

Lineage for d4cxaa_ (4cxa A:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d4cxaa_: 4cxa A: [262648]
   Other proteins in same PDB: d4cxab1, d4cxab2, d4cxad1, d4cxad2
   automated match to d4un0c_
   complexed with anp

Details for d4cxaa_

PDB Entry: 4cxa, 3.15 Å

PDB Description: crystal structure of the human cdk12-cyclin k complex bound to amppnp

PDB Compounds: (A:) cyclin-dependent kinase 12

SCOPe Domain Sequences for d4cxaa_:

Sequence, based on SEQRES records:

>d4cxaa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dwgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitaireiki
lrqlihrsvvnmkeivtdkqdaldfkkdkgafylvfeymdhdlmgllesglvhfsedhik
sfmkqlmegleychkknflhrdikcsnillnnsgqikladfglarlynseesrpytnkvi
tlwyrppelllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcp
avwpdviklpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqs
dflkdvelskmappdlphwqdchelwskkrrrq

Sequence, based on observed residues (ATOM records):

>d4cxaa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dwgkrcvdkfdiigiigegtygqvykakdkdtgelvalkkvrldnekegfpitaireiki
lrqlihrsvvnmkeivtdkqldfkkdkgafylvfeymdhdlmgllesglvhfsedhiksf
mkqlmegleychkknflhrdikcsnillnnsgqikladfglarlynseerpytnkvitlw
yrppelllgeerytpaidvwscgcilgelftkkpifqanlelaqlelisrlcgspcpavw
pdviklpyfntmkpkkqyrrrlreefsfipsaaldlldhmltldpskrctaeqtlqsdfl
kdvelskmappdlphwqdchelwskkrrrq

Timeline for d4cxaa_:

• d4cxaa_ first appeared in SCOPe 2.05
  
• d4cxaa_ appears in SCOPe 2.07
  
• d4cxaa_ appears in the current release, SCOPe 2.08