SCOPe 2.07: Domain d3crka2: 3crk A:185-402

Lineage for d3crka2 (3crk A:185-402)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.122: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55873] (1 superfamily)
   8-stranded mixed beta-sheet; 2 layers: alpha/beta

4. Superfamily d.122.1: ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase [55874] (5 families)

5. Family d.122.1.4: alpha-ketoacid dehydrogenase kinase, C-terminal domain [69804] (3 proteins)

6. Protein automated matches [230554] (2 species)
   not a true protein

7. Species Norway rat (Rattus norvegicus) [TaxId:10116] [233755] (2 PDB entries)

8. Domain d3crka2: 3crk A:185-402 [262273]
   Other proteins in same PDB: d3crka1, d3crkb1, d3crkc_, d3crkd_
   automated match to d4mpca2
   complexed with k

Details for d3crka2

PDB Entry: 3crk, 2.3 Å

PDB Description: crystal structure of the pdhk2-l2 complex.

PDB Compounds: (A:) Pyruvate dehydrogenase [lipoamide] kinase isozyme 2, mitochondrial

SCOPe Domain Sequences for d3crka2:

Sequence, based on SEQRES records:

>d3crka2 d.122.1.4 (A:185-402) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
pkhigsidpncsvsdvvkdaydmakllcdkyymaspdleiqevnatnatqpihmvyvpsh
lyhmlfelfknamratveshessltlppikimvalgeedlsikmsdrgggvplrkierlf
symystaptpqpgtggtplagfgyglpisrlyakyfqgdlqlfsmegfgtdaviylkals
tdsverlpvynksawrhyqtiqeagdwcvpstepknts

Sequence, based on observed residues (ATOM records):

>d3crka2 d.122.1.4 (A:185-402) automated matches {Norway rat (Rattus norvegicus) [TaxId: 10116]}
pkhigsidpncsvsdvvkdaydmakllcdkyymaspdleiqevnatnatqpihmvyvpsh
lyhmlfelfknamratveshessltlppikimvalgeedlsikmsdrgggvplrkierlf
symystapgyglpisrlyakyfqgdlqlfsmegfgtdaviylkalstdsverlpvynksa
wrhyqtiqeagdwcvpstepknts

Timeline for d3crka2:

• d3crka2 first appeared in SCOPe 2.05
  
• d3crka2 appears in SCOPe 2.06
  
• d3crka2 appears in the current release, SCOPe 2.08