SCOPe 2.05: Domain d1yc0a_: 1yc0 A:

Lineage for d1yc0a_ (1yc0 A:)

1. Root: SCOPe 2.05

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Hepatocyte growth factor activator, HGFA [267665] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [267750] (2 PDB entries)

8. Domain d1yc0a_: 1yc0 A: [262183]
   Other proteins in same PDB: d1yc0i_
   automated match to d1ybwa_
   complexed with po4

Details for d1yc0a_

PDB Entry: 1yc0, 2.6 Å

PDB Description: short form HGFA with first Kunitz domain from HAI-1

PDB Compounds: (A:) Hepatocyte growth factor activator

SCOPe Domain Sequences for d1yc0a_:

Sequence, based on SEQRES records:

>d1yc0a_ b.47.1.2 (A:) Hepatocyte growth factor activator, HGFA {Human (Homo sapiens) [TaxId: 9606]}
acgrrhkkrtflrpriiggssslpgshpwlaaiyigdsfcagslvhtcwvvsaahcfshs
pprdsvsvvlgqhffnrttdvtqtfgiekyipytlysvfnpsdhdlvlirlkkkgdrcat
rsqfvqpiclpepgstfpaghkcqiagwghldenvsgyssslrealvplvadhkcsspev
ygadispnmlcagyfdcksdacqgdsggplacekngvaylygiiswgdgcgrlhkpgvyt
rvanyvdwindrir

Sequence, based on observed residues (ATOM records):

>d1yc0a_ b.47.1.2 (A:) Hepatocyte growth factor activator, HGFA {Human (Homo sapiens) [TaxId: 9606]}
acgrrhkkiiggssslpgshpwlaaiyigdsfcagslvhtcwvvsaahcfshspprdsvs
vvlgqhffnrttdvtqtfgiekyipytlysvfnpsdhdlvlirlkkkgdrcatrsqfvqp
iclpepgstfpaghkcqiagwghldenvsgyssslrealvplvadhkcsspevygadisp
nmlcagyfdcksdacqgdsggplacekngvaylygiiswgdgcgrlhkpgvytrvanyvd
windrir

Timeline for d1yc0a_:

• d1yc0a_ is new in SCOPe 2.05-stable
  
• d1yc0a_ appears in SCOPe 2.06
  
• d1yc0a_ appears in the current release, SCOPe 2.08