Lineage for d4wwoa3 (4wwo A:545-725)

  1. Root: SCOPe 2.07
  2. 2299346Class a: All alpha proteins [46456] (289 folds)
  3. 2332674Fold a.118: alpha-alpha superhelix [48370] (28 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2332675Superfamily a.118.1: ARM repeat [48371] (27 families) (S)
  5. 2332885Family a.118.1.6: Phoshoinositide 3-kinase (PI3K) helical domain [48399] (1 protein)
    automatically mapped to Pfam PF00613
  6. 2332886Protein Phoshoinositide 3-kinase (PI3K) helical domain [48400] (2 species)
  7. 2332887Species Human (Homo sapiens) [TaxId:9606] [48402] (68 PDB entries)
  8. 2332914Domain d4wwoa3: 4wwo A:545-725 [262152]
    Other proteins in same PDB: d4wwoa1, d4wwoa2, d4wwoa4
    automated match to d1e7ua1
    complexed with 3vd, so4

Details for d4wwoa3

PDB Entry: 4wwo (more details), 2.3 Å

PDB Description: crystal structure of human pi3k-gamma in complex with phenylquinoline inhibitor n-{(1s)-1-[8-chloro-2-(3-fluorophenyl)quinolin-3-yl]ethyl}- 9h-purin-6-amine
PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d4wwoa3:

Sequence; same for both SEQRES and ATOM records: (download)

>d4wwoa3 a.118.1.6 (A:545-725) Phoshoinositide 3-kinase (PI3K) helical domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4wwoa3:

Click to download the PDB-style file with coordinates for d4wwoa3.
(The format of our PDB-style files is described here.)

Timeline for d4wwoa3: