Lineage for d4wwpa3 (4wwp A:546-725)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 2006336Fold a.118: alpha-alpha superhelix [48370] (25 superfamilies)
    multihelical; 2 (curved) layers: alpha/alpha; right-handed superhelix
  4. 2006337Superfamily a.118.1: ARM repeat [48371] (26 families) (S)
  5. 2006533Family a.118.1.6: Phoshoinositide 3-kinase (PI3K) helical domain [48399] (1 protein)
    automatically mapped to Pfam PF00613
  6. 2006534Protein Phoshoinositide 3-kinase (PI3K) helical domain [48400] (2 species)
  7. 2006535Species Human (Homo sapiens) [TaxId:9606] [48402] (59 PDB entries)
  8. 2006555Domain d4wwpa3: 4wwp A:546-725 [262144]
    Other proteins in same PDB: d4wwpa1, d4wwpa2, d4wwpa4
    automated match to d1e7ua1
    complexed with 3ve, gol, so4

Details for d4wwpa3

PDB Entry: 4wwp (more details), 2.4 Å

PDB Description: Crystal structure of human PI3K-gamma in complex with pyridinylquinoline inhibitor N-{(1S)-1-[8-chloro-2-(2-methylpyridin-3-yl)quinolin-3-yl]ethyl}-9H-purin-6-amine
PDB Compounds: (A:) Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform

SCOPe Domain Sequences for d4wwpa3:

Sequence; same for both SEQRES and ATOM records: (download)

>d4wwpa3 a.118.1.6 (A:546-725) Phoshoinositide 3-kinase (PI3K) helical domain {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4wwpa3:

Click to download the PDB-style file with coordinates for d4wwpa3.
(The format of our PDB-style files is described here.)

Timeline for d4wwpa3: