SCOP 1.57: Domain d1ycp.1: 1ycp L:,H:

Lineage for d1ycp.1 (1ycp L:,H:)

1. Root: SCOP 1.57

2. Class b: All beta proteins [48724] (104 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (35 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Cow (Bos taurus) [TaxId:9913] [50533] (19 PDB entries)

8. Domain d1ycp.1: 1ycp L:,H: [26214]

Details for d1ycp.1

PDB Entry: 1ycp, 2.5 Å

PDB Description: the crystal structure of fibrinogen-aa peptide 1-23 (f8y) bound to bovine thrombin explains why the mutation of phe-8 to tyrosine strongly inhibits normal cleavage at arginine-16

SCOP Domain Sequences for d1ycp.1:

Sequence, based on SEQRES records:

>g1ycp.1 b.47.1.2 (L:,H:) Thrombin {Cow (Bos taurus)}
adcglrplfekkqvqdqtekelfesyiegXivegqdaevglspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftvddllvrigkhsrtryerkvekismldkiyihpry
nwkenldrdiallklkrpielsdyihpvclpdkqtaakllhagfkgrvtgwgnrretwtt
svaevqpsvlqvvnlplverpvckastriritdnmfcagykpgegkrgdacegdsggpfv
mkspynnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvid

Sequence, based on observed residues (ATOM records):

>g1ycp.1 b.47.1.2 (L:,H:) Thrombin {Cow (Bos taurus)}
adcglrplfekkqvqdqtekelfesyiegXivegqdaevglspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftvddllvrigkhsrtryerkvekismldkiyihpry
nwkenldrdiallklkrpielsdyihpvclpdkqtaakllhagfkgrvtgwgnrrevqps
vlqvvnlplverpvckastriritdnmfcagykpgegkrgdacegdsggpfvmkspynnr
wyqmgivswgegcdrdgkygfythvfrlkkwiqkvid

Timeline for d1ycp.1:

• d1ycp.1 first appeared (with stable ids) in SCOP 1.55
  
• d1ycp.1 appears in SCOP 1.59
  
• d1ycp.1 appears in the current release, SCOPe 2.08