SCOPe 2.01: Domain d1mkxk_: 1mkx K:

Lineage for d1mkxk_ (1mkx K:)

1. Root: SCOPe 2.01

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Cow (Bos taurus) [TaxId:9913] [50533] (26 PDB entries)
   Uniprot P00734 333-622

8. Domain d1mkxk_: 1mkx K: [26204]
   chain K is pretrombin-2

Details for d1mkxk_

PDB Entry: 1mkx, 2.2 Å

PDB Description: the co-crystal structure of unliganded bovine alpha-thrombin and prethrombin-2: movement of the yppw segment and active site residues upon ligand binding

PDB Compounds: (K:) prethrombin-2

SCOPe Domain Sequences for d1mkxk_:

Sequence; same for both SEQRES and ATOM records:

>d1mkxk_ b.47.1.2 (K:) Thrombin {Cow (Bos taurus) [TaxId: 9913]}
geadcglrplfekkqvqdqtekelfesyiegrivegqdaevglspwqvmlfrkspqellc
gaslisdrwvltaahcllyppwdknftvddllvrigkhsrtryerkvekismldkiyihp
rynwkenldrdiallklkrpielsdyihpvclpdkqtaakllhagfkgrvtgwgnrretw
ttsvaevqpsvlqvvnlplverpvckastriritdnmfcagykpgegkrgdacegdsggp
fvmkspynnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvid

Timeline for d1mkxk_:

• d1mkxk_ first appeared (with stable ids) in SCOP 1.55
  
• d1mkxk_ appears in SCOP 1.75
  
• d1mkxk_ appears in SCOPe 2.02
  
• d1mkxk_ appears in the current release, SCOPe 2.08