SCOPe 2.06: Domain d4tpmb_: 4tpm B:

Lineage for d4tpmb_ (4tpm B:)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (6 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (9 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (111 PDB entries)

8. Domain d4tpmb_: 4tpm B: [261986]
   automated match to d2ourb_
   complexed with 35e, gol, so4, zn

Details for d4tpmb_

PDB Entry: 4tpm, 2.77 Å

PDB Description: crystal structure of 2-(3-alkoxy-1-azetidinyl) quinolines as pde10a inhibitors

PDB Compounds: (B:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d4tpmb_:

Sequence; same for both SEQRES and ATOM records:

>d4tpmb_ a.211.1.0 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvkknyrrv
pyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylqkfdhpl
aalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnr
kqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegde
mkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnlsqw
ekvirge

Timeline for d4tpmb_:

• d4tpmb_ first appeared in SCOPe 2.04
  
• d4tpmb_ appears in SCOPe 2.05
  
• d4tpmb_ appears in SCOPe 2.07
  
• d4tpmb_ appears in the current release, SCOPe 2.08