Lineage for d4q1ea_ (4q1e A:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2109203Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
    3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes
  4. 2109204Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families) (S)
    division into families based on beta-sheet topologies
  5. 2109205Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 protein domains)
    parallel beta-sheet of 5 strands, order 23145
  6. 2109296Protein Deoxycytidine kinase [89657] (1 species)
  7. 2109297Species Human (Homo sapiens) [TaxId:9606] [89658] (45 PDB entries)
  8. 2109326Domain d4q1ea_: 4q1e A: [261893]
    automated match to d4jlnb_
    complexed with 2y7, 2y8, udp; mutant

Details for d4q1ea_

PDB Entry: 4q1e (more details), 1.85 Å

PDB Description: Human dCK C4S-S74E mutant in complex with UDP and the inhibitor 10 {2-{[(1R/S)-1-{2-[3-(2-fluoroethoxy)-4-methoxyphenyl]-5-methyl-1,3-thiazol 4-yl}ethyl]sulfanyl}pyrimidine-4,6-diamine}
PDB Compounds: (A:) Deoxycytidine kinase

SCOPe Domain Sequences for d4q1ea_:

Sequence, based on SEQRES records: (download)

>d4q1ea_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}

Sequence, based on observed residues (ATOM records): (download)

>d4q1ea_ c.37.1.1 (A:) Deoxycytidine kinase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4q1ea_:

Click to download the PDB-style file with coordinates for d4q1ea_.
(The format of our PDB-style files is described here.)

Timeline for d4q1ea_: