SCOP 1.69: Domain d1hap.1: 1hap L:,H:

Lineage for d1hap.1 (1hap L:,H:)

1. Root: SCOP 1.69

2. Class b: All beta proteins [48724] (144 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (46 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (155 PDB entries)

8. Domain d1hap.1: 1hap L:,H: [26187]

Details for d1hap.1

PDB Entry: 1hap, 2.8 Å

PDB Description: complex of human alpha-thrombin with a 15mer oligonucleotide ggttggtgtggttgg (based on x-ray model of dna)

SCOP Domain Sequences for d1hap.1:

Sequence, based on SEQRES records:

>g1hap.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens)}
adcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtanv
gkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmk
spfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Sequence, based on observed residues (ATOM records):

>g1hap.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens)}
adcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwgqps
vlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnr
wyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Timeline for d1hap.1:

• d1hap.1 first appeared (with stable ids) in SCOP 1.55
  
• d1hap.1 appears in SCOP 1.67
  
• d1hap.1 appears in SCOP 1.71
  
• d1hap.1 appears in the current release, SCOPe 2.08