SCOP 1.73: Domain d1hlt.1: 1hlt L:,H:

Lineage for d1hlt.1 (1hlt L:,H:)

1. Root: SCOP 1.73

2. Class b: All beta proteins [48724] (165 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (163 PDB entries)

8. Domain d1hlt.1: 1hlt L:,H: [26181]

Details for d1hlt.1

PDB Entry: 1hlt, 3 Å

PDB Description: the structure of a nonadecapeptide of the fifth egf domain of thrombomodulin complexed with thrombin

PDB Compounds: (H:) alpha-thrombin (large subunit), (L:) alpha-thrombin (small subunit)

SCOP Domain Sequences for d1hlt.1:

Sequence, based on SEQRES records:

>g1hlt.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
adcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtanv
gkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmk
spfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidq

Sequence, based on observed residues (ATOM records):

>g1hlt.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
adcglrplfekksledkterellesyiXivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtgqp
svlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnn
rwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidq

Timeline for d1hlt.1:

• d1hlt.1 first appeared (with stable ids) in SCOP 1.55
  
• d1hlt.1 appears in SCOP 1.71
  
• d1hlt.1 appears in SCOP 1.75
  
• d1hlt.1 appears in the current release, SCOPe 2.08