Lineage for d3sqpa2 (3sqp A:166-290)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2096453Fold c.3: FAD/NAD(P)-binding domain [51904] (1 superfamily)
    core: 3 layers, b/b/a; central parallel beta-sheet of 5 strands, order 32145; top antiparallel beta-sheet of 3 strands, meander
  4. 2096454Superfamily c.3.1: FAD/NAD(P)-binding domain [51905] (9 families) (S)
  5. 2096984Family c.3.1.5: FAD/NAD-linked reductases, N-terminal and central domains [51943] (15 protein domains)
    duplication: both domains have similar folds and functions
    most members of the family contain common C-terminal alpha+beta domain
  6. 2097072Protein Glutathione reductase [51944] (3 species)
  7. 2097090Species Human (Homo sapiens) [TaxId:9606] [51945] (23 PDB entries)
  8. 2097128Domain d3sqpa2: 3sqp A:166-290 [261746]
    Other proteins in same PDB: d3sqpa3, d3sqpb3
    automated match to d3grsa2
    protein/RNA complex; complexed with 3j8, fad, gol, so4

Details for d3sqpa2

PDB Entry: 3sqp (more details), 2.21 Å

PDB Description: Structure of human glutathione reductase complexed with pyocyanin, an agent with antimalarial activity
PDB Compounds: (A:) glutathione reductase, mitochondrial

SCOPe Domain Sequences for d3sqpa2:

Sequence; same for both SEQRES and ATOM records: (download)

>d3sqpa2 c.3.1.5 (A:166-290) Glutathione reductase {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d3sqpa2:

Click to download the PDB-style file with coordinates for d3sqpa2.
(The format of our PDB-style files is described here.)

Timeline for d3sqpa2: