SCOP 1.61: Domain d3hat.1: 3hat L:,H:

Lineage for d3hat.1 (3hat L:,H:)

1. Root: SCOP 1.61

2. Class b: All beta proteins [48724] (111 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (38 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (130 PDB entries)

8. Domain d3hat.1: 3hat L:,H: [26163]

Details for d3hat.1

PDB Entry: 3hat, 2.5 Å

PDB Description: active site mimetic inhibition of thrombin

SCOP Domain Sequences for d3hat.1:

Sequence, based on SEQRES records:

>g3hat.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens)}
tfgsgeadcglrplfekksledkterellesyidgrXivegsdaeigmspwqvmlfrksp
qellcgaslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlek
iyihprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgn
lketwtanvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdaceg
dsggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Sequence, based on observed residues (ATOM records):

>g3hat.1 b.47.1.2 (L:,H:) Thrombin {Human (Homo sapiens)}
tfgsgeadcglrplfekksledkterellesyidgrXivegsdaeigmspwqvmlfrksp
qellcgaslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlek
iyihprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgn
lkegqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvm
kspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Timeline for d3hat.1:

• d3hat.1 first appeared (with stable ids) in SCOP 1.55
  
• d3hat.1 appears in SCOP 1.59
  
• d3hat.1 appears in SCOP 1.63
  
• d3hat.1 appears in the current release, SCOPe 2.08