SCOPe 2.04: Domain d1d9ia_: 1d9i A:

Lineage for d1d9ia_ (1d9i A:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (169 PDB entries)
   Uniprot P00734 331-361,364-421 ! Uniprot P00734 334-360 364-510 518-619 ! Uniprot P00734 328-620 ! Uniprot P00734 355-621 ! Uniprot P00734 328-620

8. Domain d1d9ia_: 1d9i A: [26159]
   complexed with 00p, na

Details for d1d9ia_

PDB Entry: 1d9i, 2.3 Å

PDB Description: structure of thrombin complexed with selective non-electophilic inhibitors having cyclohexyl moieties at p1

PDB Compounds: (A:) thrombin

SCOPe Domain Sequences for d1d9ia_:

Sequence, based on SEQRES records:

>d1d9ia_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
adcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcga
slisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpry
nwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwta
nvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfv
mkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

Sequence, based on observed residues (ATOM records):

>d1d9ia_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
adcglrplfekksledkterellesyidivegsdaeigmspwqvmlfrkspqellcgasl
isdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynw
renldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketgqpsv
lqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrw
yqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

Timeline for d1d9ia_:

• d1d9ia_ first appeared (with stable ids) in SCOP 1.55
  
• d1d9ia_ appears in SCOPe 2.03
  
• d1d9ia_ appears in SCOPe 2.05
  
• d1d9ia_ appears in the current release, SCOPe 2.08