SCOPe 2.07: Domain d3wn5a1: 3wn5 A:233-339

Lineage for d3wn5a1 (3wn5 A:233-339)

1. Root: SCOPe 2.07

2. Class b: All beta proteins [48724] (178 folds)

3. Fold b.1: Immunoglobulin-like beta-sandwich [48725] (33 superfamilies)
   sandwich; 7 strands in 2 sheets; greek-key
   some members of the fold have additional strands

4. Superfamily b.1.1: Immunoglobulin [48726] (5 families)

5. Family b.1.1.2: C1 set domains (antibody constant domain-like) [48942] (24 proteins)

6. Protein Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma [88584] (4 species)

7. Species Human (Homo sapiens) [TaxId:9606] [88585] (61 PDB entries)
   Uniprot P01857 #118-327 ! Uniprot P01857 118-327 # GC1_HUMAN Ig gamma-1 chain C region

8. Domain d3wn5a1: 3wn5 A:233-339 [261193]
   Other proteins in same PDB: d3wn5a2, d3wn5b2, d3wn5c1, d3wn5c2, d3wn5d2, d3wn5e2, d3wn5f1, d3wn5f2
   automated match to d1hzhh3
   complexed with iod, nag

Details for d3wn5a1

PDB Entry: 3wn5, 2.78 Å

PDB Description: crystal structure of asymmetrically engineered fc variant in complex with fcgriiia

PDB Compounds: (A:) Ig gamma-1 chain C region

SCOPe Domain Sequences for d3wn5a1:

Sequence; same for both SEQRES and ATOM records:

>d3wn5a1 b.1.1.2 (A:233-339) Immunoglobulin heavy chain gamma constant domain 2, CH2-gamma {Human (Homo sapiens) [TaxId: 9606]}
ellggpsvflfppkpkdtlmisrtpevtcvvvdvsheepevkfnwyvdgvevhnaktkpr
eeqynstyrvvsvltvlhqdwlngkeykckvsndalpkpieetiska

Timeline for d3wn5a1:

• d3wn5a1 first appeared in SCOPe 2.04
  
• d3wn5a1 appears in SCOPe 2.06
  
• d3wn5a1 appears in the current release, SCOPe 2.08