SCOP 1.71: Domain d1bb0.1: 1bb0 A:,B:

Lineage for d1bb0.1 (1bb0 A:,B:)

1. Root: SCOP 1.71

2. Class b: All beta proteins [48724] (149 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (157 PDB entries)

8. Domain d1bb0.1: 1bb0 A:,B: [26106]
   complexed with 3ga, na, pms, ron

Details for d1bb0.1

PDB Entry: 1bb0, 2.1 Å

PDB Description: thrombin inhibitors with rigid tripeptidyl aldehydes

SCOP Domain Sequences for d1bb0.1:

Sequence, based on SEQRES records:

>g1bb0.1 b.47.1.2 (A:,B:) Thrombin {Human (Homo sapiens)}
adcglrplfekksledkterellesyXivegsdaeigmspwqvmlfrkspqellcgasli
sdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynwr
enldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwtanvg
kgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmks
pfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfg

Sequence, based on observed residues (ATOM records):

>g1bb0.1 b.47.1.2 (A:,B:) Thrombin {Human (Homo sapiens)}
adcglrplfekksledkterellesyXivegsdaeigmspwqvmlfrkpqellcgaslis
drwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihprynwre
nldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlkegqpsvlqv
vnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsggpfvmkspfnnrwyqm
givswgegcdrdgkygfythvfrlkkwiqkvidqfg

Timeline for d1bb0.1:

• d1bb0.1 first appeared (with stable ids) in SCOP 1.55
  
• d1bb0.1 appears in SCOP 1.69
  
• d1bb0.1 appears in SCOP 1.73
  
• d1bb0.1 appears in the current release, SCOPe 2.08