SCOPe 2.07: Domain d4nifa_: 4nif A:

Lineage for d4nifa_ (4nif A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (35 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1319 PDB entries)

8. Domain d4nifa_: 4nif A: [260918]
   Other proteins in same PDB: d4nifb_, d4nife_
   automated match to d2ozaa_
   complexed with anp, na, so4

Details for d4nifa_

PDB Entry: 4nif, 2.15 Å

PDB Description: heterodimeric structure of erk2 and rsk1

PDB Compounds: (A:) Ribosomal protein S6 kinase alpha-1

SCOPe Domain Sequences for d4nifa_:

Sequence, based on SEQRES records:

>d4nifa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vfsdgyvvketigvgsyseckrcvhkatnmeyavkvidkskrdpseeieillrygqhpni
itlkdvyddgkhvylvtelmrggelldkilrqkffsereasfvlhtigktveylhsqgvv
hrdlkpsnilyvdesgnpeclricdfgfakqlraengllmtpcytanfvapevlkrqgyd
egcdiwslgillytmlagytpfangpsdtpeeiltrigsgkftlsggnwntvsetakdlv
skmlhvdphqrltakqvlqhpwvtqkdklpqsqlshqdlqlvkgamaatysalnsskptp
qlkpiessilaqrrvr

Sequence, based on observed residues (ATOM records):

>d4nifa_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vfsdgyvvketigvgsyseckrcvhkatnmeyavkvidkskrdpseeieillrygqhpni
itlkdvyddgkhvylvtelmrggelldkilrqkffsereasfvlhtigktveylhsqgvv
hrdlkpsnilyvdesgnpeclricdfgfakqlraengllmtpcyfvapevlkrqgydegc
diwslgillytmlagytpfangpsdtpeeiltrigsgkftlsggnwntvsetakdlvskm
lhvdphqrltakqvlqhpwvtqkdklpqsqlshqdlqlvkgamaatysalnsskptpqlk
piessilaqrrvr

Timeline for d4nifa_:

• d4nifa_ first appeared in SCOPe 2.04
  
• d4nifa_ appears in SCOPe 2.06
  
• d4nifa_ appears in the current release, SCOPe 2.08