Lineage for d4i5ia_ (4i5i A:)

  1. Root: SCOPe 2.07
  2. 2413226Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2444630Fold c.31: DHS-like NAD/FAD-binding domain [52466] (1 superfamily)
    3 layers: a/b/a; parallel beta-sheet of 6 strands, order 321456; Rossmann-like
  4. 2444631Superfamily c.31.1: DHS-like NAD/FAD-binding domain [52467] (7 families) (S)
    binds cofactor molecules in the opposite direction than classical Rossmann fold
  5. 2445027Family c.31.1.0: automated matches [191352] (1 protein)
    not a true family
  6. 2445028Protein automated matches [190312] (11 species)
    not a true protein
  7. 2445047Species Human (Homo sapiens) [TaxId:9606] [224883] (17 PDB entries)
  8. 2445073Domain d4i5ia_: 4i5i A: [260889]
    automated match to d4ig9g_
    complexed with 4i5, nad, zn

Details for d4i5ia_

PDB Entry: 4i5i (more details), 2.5 Å

PDB Description: Crystal structure of the SIRT1 catalytic domain bound to NAD and an EX527 analog
PDB Compounds: (A:) NAD-dependent protein deacetylase sirtuin-1

SCOPe Domain Sequences for d4i5ia_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4i5ia_ c.31.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4i5ia_:

Click to download the PDB-style file with coordinates for d4i5ia_.
(The format of our PDB-style files is described here.)

Timeline for d4i5ia_: