Lineage for d4wiva1 (4wiv A:44-168)

  1. Root: SCOPe 2.06
  2. 1976409Class a: All alpha proteins [46456] (289 folds)
  3. 1992366Fold a.29: Bromodomain-like [47363] (15 superfamilies)
    4 helices; bundle; minor mirror variant of up-and-down topology
  4. 1992367Superfamily a.29.2: Bromodomain [47370] (2 families) (S)
  5. 1992467Family a.29.2.0: automated matches [191428] (1 protein)
    not a true family
  6. 1992468Protein automated matches [190615] (7 species)
    not a true protein
  7. 1992472Species Human (Homo sapiens) [TaxId:9606] [187641] (355 PDB entries)
  8. 1992665Domain d4wiva1: 4wiv A:44-168 [260854]
    Other proteins in same PDB: d4wiva2
    automated match to d3u5la_
    complexed with 3p2, edo, gol

Details for d4wiva1

PDB Entry: 4wiv (more details), 1.56 Å

PDB Description: crystal structure of the first bromodomain of human brd4 in complex with a novel inhibitor umb32 (n-tert-butyl-2-[4-(3,5-dimethyl-1,2- oxazol-4-yl) phenyl]imidazo[1,2-a]pyrazin-3-amine)
PDB Compounds: (A:) Bromodomain-containing protein 4

SCOPe Domain Sequences for d4wiva1:

Sequence; same for both SEQRES and ATOM records: (download)

>d4wiva1 a.29.2.0 (A:44-168) automated matches {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4wiva1:

Click to download the PDB-style file with coordinates for d4wiva1.
(The format of our PDB-style files is described here.)

Timeline for d4wiva1:

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