SCOPe 2.04: Domain d4rn6b_: 4rn6 B:

Lineage for d4rn6b_ (4rn6 B:)

1. Root: SCOPe 2.04

2. Class b: All beta proteins [48724] (176 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (48 proteins)

6. Protein automated matches [190044] (14 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187233] (136 PDB entries)

8. Domain d4rn6b_: 4rn6 B: [260811]
   automated match to d3sqhe_
   complexed with 15u; mutant

Details for d4rn6b_

PDB Entry: 4rn6, 3 Å

PDB Description: Structure of prethrombin-2 mutant s195a bound to the active site inhibitor argatroban

PDB Compounds: (B:) Thrombin heavy chain

SCOPe Domain Sequences for d4rn6b_:

Sequence, based on SEQRES records:

>d4rn6b_ b.47.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eadcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcg
aslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpr
ynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwt
anvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdaggpf
vmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Sequence, based on observed residues (ATOM records):

>d4rn6b_ b.47.1.2 (B:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
eadcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspqellcg
aslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyihpr
ynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlketwt
apsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdaggpfvmkspf
nnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Timeline for d4rn6b_:

• d4rn6b_ is new in SCOPe 2.04-stable
  
• d4rn6b_ appears in SCOPe 2.05
  
• d4rn6b_ appears in the current release, SCOPe 2.08