SCOP 1.75: Domain d1doja_: 1doj A:

Lineage for d1doja_ (1doj A:)

1. Root: SCOP 1.75

2. Class b: All beta proteins [48724] (174 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (4 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (47 proteins)

6. Protein Thrombin [50531] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [50532] (164 PDB entries)
   Uniprot P00734 331-361,364-421
   Uniprot P00734 334-360 364-510 518-619
   Uniprot P00734 328-620
   Uniprot P00734 355-621
   Uniprot P00734 328-620
   Uniprot P00734 331-361,364-421 ! Uniprot P00734 334-360 364-510 518-619 ! Uniprot P00734 328-620 ! Uniprot P00734 355-621 ! Uniprot P00734 328-620

8. Domain d1doja_: 1doj A: [26081]
   complexed with ar2, ch3, na, nag

Details for d1doja_

PDB Entry: 1doj, 1.7 Å

PDB Description: crystal structure of human alpha-thrombin*rwj-51438 complex at 1.7 a

PDB Compounds: (A:) alpha-thrombin

SCOP Domain Sequences for d1doja_:

Sequence, based on SEQRES records:

>d1doja_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
tfgsgeadcglrplfekksledkterellesyidgrivegsdaeigmspwqvmlfrkspq
ellcgaslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismleki
yihprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnl
ketwtanvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegd
sggpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Sequence, based on observed residues (ATOM records):

>d1doja_ b.47.1.2 (A:) Thrombin {Human (Homo sapiens) [TaxId: 9606]}
tfgsgeadcglrplfekksledkterellesyidivegsdaeigmspwqvmlfrkspqel
lcgaslisdrwvltaahcllyppwdknftendllvrigkhsrtryerniekismlekiyi
hprynwrenldrdialmklkkpvafsdyihpvclpdretaasllqagykgrvtgwgnlke
twtanvgkgqpsvlqvvnlpiverpvckdstriritdnmfcagykpdegkrgdacegdsg
gpfvmkspfnnrwyqmgivswgegcdrdgkygfythvfrlkkwiqkvidqfge

Timeline for d1doja_:

• d1doja_ first appeared (with stable ids) in SCOP 1.55
  
• d1doja_ appears in SCOP 1.73
  
• d1doja_ appears in SCOPe 2.01
  
• d1doja_ appears in the current release, SCOPe 2.08