SCOPe 2.08: Domain d4uy1a_: 4uy1 A:

Lineage for d4uy1a_ (4uy1 A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.133: Phospholipase A2, PLA2 [48618] (1 superfamily)
   common core: 2 helices, disulfide-linked, and a calcium-binding loop

4. Superfamily a.133.1: Phospholipase A2, PLA2 [48619] (4 families)

5. Family a.133.1.2: Vertebrate phospholipase A2 [48623] (3 proteins)
   automatically mapped to Pfam PF00068

6. Protein automated matches [190139] (27 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [260458] (12 PDB entries)

8. Domain d4uy1a_: 4uy1 A: [260459]
   automated match to d1le6a_
   complexed with 1pe, ca, dms, peg, tjm

Details for d4uy1a_

PDB Entry: 4uy1, 2.2 Å

PDB Description: novel pyrazole series of group x secretory phospholipase a2 (spla2-x) inhibitors

PDB Compounds: (A:) group 10 secretory phospholipase a2

SCOPe Domain Sequences for d4uy1a_:

Sequence; same for both SEQRES and ATOM records:

>d4uy1a_ a.133.1.2 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
gilelagtvgcvgprtpiaymkygcfcglgghgqprdaidwcchghdccytraeeagcsp
kteryswqcvnqsvlcgpaenkcqellckcdqeianclaqteynlkylfypqflcepdsp
kc

Timeline for d4uy1a_:

• d4uy1a_ first appeared in SCOPe 2.04
  
• d4uy1a_ appears in SCOPe 2.07