SCOPe 2.05: Domain d3wv3a_: 3wv3 A:

Lineage for d3wv3a_ (3wv3 A:)

1. Root: SCOPe 2.05

2. Class d: Alpha and beta proteins (a+b) [53931] (381 folds)

3. Fold d.92: Zincin-like [55485] (2 superfamilies)
   contains mixed beta sheet with connection over free side of the sheet

4. Superfamily d.92.1: Metalloproteases ("zincins"), catalytic domain [55486] (18 families)

5. Family d.92.1.11: Matrix metalloproteases, catalytic domain [55528] (14 proteins)

6. Protein Collagenase-3 (MMP-13) [55540] (2 species)

7. Species Human (Homo sapiens) [TaxId:9606] [55541] (40 PDB entries)

8. Domain d3wv3a_: 3wv3 A: [260128]
   automated match to d1euba_
   complexed with ca, edo, fmt, na, wll, zn

Details for d3wv3a_

PDB Entry: 3wv3, 1.6 Å

PDB Description: crystal structure of the catalytic domain of mmp-13 complexed with n- (3-methoxybenzyl)-4-oxo-3,4-dihydrothieno[2,3-d]pyrimidine-2- carboxamide

PDB Compounds: (A:) collagenase 3

SCOPe Domain Sequences for d3wv3a_:

Sequence, based on SEQRES records:

>d3wv3a_ d.92.1.11 (A:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytytgkshfmlpdddvqgiqslygpgdedp

Sequence, based on observed residues (ATOM records):

>d3wv3a_ d.92.1.11 (A:) Collagenase-3 (MMP-13) {Human (Homo sapiens) [TaxId: 9606]}
ynvfprtlkwskmnltyrivnytpdmthsevekafkkafkvwsdvtplnftrlhdgiadi
misfgikehgdfypfdgpsgllahafppgpnyggdahfdddetwtssskgynlflvaahe
fghslgldhskdpgalmfpiytykshfmlpdddvqgiqslygpgdedp

Timeline for d3wv3a_:

• d3wv3a_ first appeared in SCOPe 2.04
  
• d3wv3a_ appears in SCOPe 2.06
  
• d3wv3a_ appears in the current release, SCOPe 2.08