Lineage for d4tnub_ (4tnu B:)

  1. Root: SCOPe 2.06
  2. 2078559Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2125386Fold c.56: Phosphorylase/hydrolase-like [53162] (8 superfamilies)
    core: 3 layers, a/b/a ; mixed sheet of 5 strands: order 21354; strand 4 is antiparallel to the rest; contains crossover loops
  4. 2126724Superfamily c.56.5: Zn-dependent exopeptidases [53187] (10 families) (S)
    core: mixed beta-sheet of 8 strands, order 12435867; strands 2, 6 & 7 are antiparallel to the rest
  5. 2127107Family c.56.5.7: AstE/AspA-like [142526] (3 protein domains)
    Pfam PF04952; Succinylglutamate desuccinylase / Aspartoacylase family; contains extra C-terminal domain, new variant of the Barrel-sandwich hybrid fold (51229)
  6. 2127108Protein Aspartoacylase AspA [159649] (2 species)
  7. 2127109Species Human (Homo sapiens) [TaxId:9606] [159651] (5 PDB entries)
    Uniprot P45381 9-310
  8. 2127119Domain d4tnub_: 4tnu B: [260033]
    automated match to d2gu2a1
    complexed with as9, zn; mutant

Details for d4tnub_

PDB Entry: 4tnu (more details), 2.9 Å

PDB Description: Human brain aspartoacylase mutant Y231C complex with intermediate analog (N-phosphonomethyl-L-aspartate)
PDB Compounds: (B:) Aspartoacylase

SCOPe Domain Sequences for d4tnub_:

Sequence; same for both SEQRES and ATOM records: (download)

>d4tnub_ c.56.5.7 (B:) Aspartoacylase AspA {Human (Homo sapiens) [TaxId: 9606]}

SCOPe Domain Coordinates for d4tnub_:

Click to download the PDB-style file with coordinates for d4tnub_.
(The format of our PDB-style files is described here.)

Timeline for d4tnub_: