SCOPe 2.06: Domain d4pjtd1: 4pjt D:663-796

Lineage for d4pjtd1 (4pjt D:663-796)

1. Root: SCOPe 2.06

2. Class a: All alpha proteins [46456] (289 folds)

3. Fold a.41: Domain of poly(ADP-ribose) polymerase [47586] (1 superfamily)
   core: 4 helices: bundle; unusual topology

4. Superfamily a.41.1: Domain of poly(ADP-ribose) polymerase [47587] (2 families)
   duplication: consists of 2 helix-loop-helix structural repeats
   automatically mapped to Pfam PF02877

5. Family a.41.1.0: automated matches [227223] (1 protein)
   not a true family

6. Protein automated matches [226964] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225405] (44 PDB entries)

8. Domain d4pjtd1: 4pjt D:663-796 [259940]
   Other proteins in same PDB: d4pjta2, d4pjtb2, d4pjtc2, d4pjtd2
   automated match to d4hhyd1
   complexed with 2yq, gol, so4

Details for d4pjtd1

PDB Entry: 4pjt, 2.35 Å

PDB Description: structure of parp1 catalytic domain bound to inhibitor bmn 673

PDB Compounds: (D:) Poly [ADP-ribose] polymerase 1

SCOPe Domain Sequences for d4pjtd1:

Sequence, based on SEQRES records:

>d4pjtd1 a.41.1.0 (D:663-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavsq
gssdsqildlsnrfytliphdfgmkkppllnnadsvqakvemldnlldievaysllrggs
ddsskdpidvnyek

Sequence, based on observed residues (ATOM records):

>d4pjtd1 a.41.1.0 (D:663-796) automated matches {Human (Homo sapiens) [TaxId: 9606]}
sklpkpvqdlikmifdvesmkkamveyeidlqkmplgklskrqiqaaysilsevqqavsl
dlsnrfytliphdppllnnadsvqakvemldnlldievaysllrdpidvnyek

Timeline for d4pjtd1:

• d4pjtd1 first appeared in SCOPe 2.04
  
• d4pjtd1 appears in SCOPe 2.05
  
• d4pjtd1 appears in SCOPe 2.07
  
• d4pjtd1 appears in the current release, SCOPe 2.08