SCOPe 2.08: Domain d4p0na_: 4p0n A:

Lineage for d4p0na_ (4p0n A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.211: HD-domain/PDEase-like [109603] (1 superfamily)
   multihelical; consists of two different alpha-helical bundles

4. Superfamily a.211.1: HD-domain/PDEase-like [109604] (9 families)

5. Family a.211.1.0: automated matches [191566] (1 protein)
   not a true family

6. Protein automated matches [190983] (12 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188676] (139 PDB entries)

8. Domain d4p0na_: 4p0n A: [259896]
   automated match to d4lm1a_
   complexed with 1ir, 1is, gol, so4, zn

Details for d4p0na_

PDB Entry: 4p0n, 2.08 Å

PDB Description: Crystal structure of PDE10a with a novel Imidazo[4,5-b]pyridine inhibitor

PDB Compounds: (A:) cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A

SCOPe Domain Sequences for d4p0na_:

Sequence; same for both SEQRES and ATOM records:

>d4p0na_ a.211.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
tlpvrlckeielfhfdigpfenmwpgifvymvhrscgtscfeleklcrfimsvkknyrrv
pyhnwkhavtvahcmyailqnnhtlftdlerkglliaclchdldhrgfsnsylqkfdhpl
aalyststmeqhhfsqtvsilqleghnifstlssseyeqvleiirkaiiatdlalyfgnr
kqleemyqtgslnlnnqshrdrviglmmtacdlcsvtklwpvtkltandiyaefwaegde
mkklgiqpipmmdrdkkdevpqgqlgfynavaipcyttltqilpptepllkacrdnlsqw
ekvirge

Timeline for d4p0na_:

• d4p0na_ first appeared in SCOPe 2.04
  
• d4p0na_ appears in SCOPe 2.07