SCOPe 2.06: Domain d4mnef_: 4mne F:

Lineage for d4mnef_ (4mne F:)

1. Root: SCOPe 2.06

2. Class d: Alpha and beta proteins (a+b) [53931] (385 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (25 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (882 PDB entries)

8. Domain d4mnef_: 4mne F: [259801]
   Other proteins in same PDB: d4mnea_, d4mned_, d4mnee_, d4mneh_
   automated match to d3bu3a_
   complexed with 573, acp, cl, mg

Details for d4mnef_

PDB Entry: 4mne, 2.85 Å

PDB Description: Crystal structure of the BRAF:MEK1 complex

PDB Compounds: (F:) Serine/threonine-protein kinase B-raf

SCOPe Domain Sequences for d4mnef_:

Sequence, based on SEQRES records:

>d4mnef_ d.144.1.0 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dweipdgqitvgqrigsgsfgtvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrkt
rhvnillfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdylh
aksiihrdlksnniflhedltvkigdfglatvksrwsgshqfeqlsgsilwmapevirmq
dknpysfqsdvyafgivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpka
mkrlmaeclkkkrderplfpqilasiellarsl

Sequence, based on observed residues (ATOM records):

>d4mnef_ d.144.1.0 (F:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
dweipdgqitvgqritvykgkwhgdvavkmlnvtaptpqqlqafknevgvlrktrhvnil
lfmgystkpqlaivtqwcegsslyhhlhiietkfemiklidiarqtaqgmdylhaksiih
rdlksnniflhedltvkigdfglatvksqlsgsilwmapevirmqdknpysfqsdvyafg
ivlyelmtgqlpysninnrdqiifmvgrgylspdlskvrsncpkamkrlmaeclkkkrde
rplfpqilasiellarsl

Timeline for d4mnef_:

• d4mnef_ first appeared in SCOPe 2.04
  
• d4mnef_ appears in SCOPe 2.05
  
• d4mnef_ appears in SCOPe 2.07
  
• d4mnef_ appears in the current release, SCOPe 2.08