SCOPe 2.08: Domain d4u2ub1: 4u2u B:23-182

Lineage for d4u2ub1 (4u2u B:23-182)

1. Root: SCOPe 2.08

2. Class f: Membrane and cell surface proteins and peptides [56835] (69 folds)

3. Fold f.1: Toxins' membrane translocation domains [56836] (5 superfamilies)
   multi-helical domains of various folds which is thought to unfold in the membrane

4. Superfamily f.1.4: Bcl-2 inhibitors of programmed cell death [56854] (2 families)
   PROVISIONAL CLASSIFICATION, based on structural similarity to the diphtheria toxin domain

5. Family f.1.4.0: automated matches [195065] (1 protein)
   not a true family

6. Protein automated matches [195066] (5 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [225196] (14 PDB entries)

8. Domain d4u2ub1: 4u2u B:23-182 [259549]
   Other proteins in same PDB: d4u2ua2, d4u2ub2
   automated match to d2imta_

Details for d4u2ub1

PDB Entry: 4u2u, 2.9 Å

PDB Description: bak domain swapped dimer induced by bidbh3 with chaps

PDB Compounds: (B:) bcl-2 homologous antagonist/killer

SCOPe Domain Sequences for d4u2ub1:

Sequence, based on SEQRES records:

>d4u2ub1 f.1.4.0 (B:23-182) automated matches {Human (Homo sapiens) [TaxId: 9606]}
seeqvaqdteevfrsyvfyrhqqeqeaegvaapadpemvtlplqpsstmgqvgrqlaiig
ddinrrydsefqtmlqhlqptaenayeyftkiatslfesginwgrvvallgfgyrlalhv
yqhgltgflgqvtrfvvdfmlhhsiarwiaqrggwvaaln

Sequence, based on observed residues (ATOM records):

>d4u2ub1 f.1.4.0 (B:23-182) automated matches {Human (Homo sapiens) [TaxId: 9606]}
seeqvaqdteevfrsyvfyrhqqeqestmgqvgrqlaiigddinrrydsefqtmlqhlqp
taenayeyftkiatslfesginwgrvvallgfgyrlalhvyqhgltgflgqvtrfvvdfm
lhhsiarwiaqrggwvaaln

Timeline for d4u2ub1:

• d4u2ub1 first appeared in SCOPe 2.04, called d4u2ub_
  
• d4u2ub1 appears in SCOPe 2.07