Lineage for d4pyja_ (4pyj A:)

  1. Root: SCOPe 2.08
  2. 2826024Class c: Alpha and beta proteins (a/b) [51349] (148 folds)
  3. 2892669Fold c.66: S-adenosyl-L-methionine-dependent methyltransferases [53334] (1 superfamily)
    core: 3 layers, a/b/a; mixed beta-sheet of 7 strands, order 3214576; strand 7 is antiparallel to the rest
  4. 2892670Superfamily c.66.1: S-adenosyl-L-methionine-dependent methyltransferases [53335] (61 families) (S)
  5. 2892671Family c.66.1.1: COMT-like [53336] (4 proteins)
  6. 2892682Protein Catechol O-methyltransferase, COMT [53337] (2 species)
  7. 2892683Species Human (Homo sapiens) [TaxId:9606] [267759] (12 PDB entries)
  8. 2892692Domain d4pyja_: 4pyj A: [259267]
    automated match to d3u81a_
    complexed with cl, mg, na

Details for d4pyja_

PDB Entry: 4pyj (more details), 1.9 Å

PDB Description: human apo-comt, single domain swap
PDB Compounds: (A:) Catechol O-methyltransferase

SCOPe Domain Sequences for d4pyja_:

Sequence, based on SEQRES records: (download)

>d4pyja_ c.66.1.1 (A:) Catechol O-methyltransferase, COMT {Human (Homo sapiens) [TaxId: 9606]}
dtkeqrilnhvlqhaepgnaqsvleaidtyceqkewamnvgdkkgkivdaviqehqpsvl
lelgaycgysavrmarllspgarlitieinpdcaaitqrmvdfagvkdkvtlvvgasqdi
ipqlkkkydvdtldmvfldhwkdrylpdtllleecgllrkgtvlladnvicpgapdflah
vrgsscfecthyqsfleyrevvdglekaiykgpg

Sequence, based on observed residues (ATOM records): (download)

>d4pyja_ c.66.1.1 (A:) Catechol O-methyltransferase, COMT {Human (Homo sapiens) [TaxId: 9606]}
dtkeqrilnhvlqhaepgnaqsvleaidtyceqkgdkkgkivdaviqehqpsvllelgay
cgysavrmarllspgarlitieinpdcaaitqrmvdfagvkdkvtlvvgasqdiipqlkk
kydvdtldmvfldhwkdrylpdtllleecgllrkgtvlladnvicpgapdflahvrgssc
fecthyqsfleyrevvdglekaiykgpg

SCOPe Domain Coordinates for d4pyja_:

Click to download the PDB-style file with coordinates for d4pyja_.
(The format of our PDB-style files is described here.)

Timeline for d4pyja_: