SCOPe 2.08: Domain d4p5za_: 4p5z A:

Lineage for d4p5za_ (4p5z A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4p5za_: 4p5z A: [259251]
   automated match to d3pp0b_
   complexed with q7m

Details for d4p5za_

PDB Entry: 4p5z, 2 Å

PDB Description: Human EphA3 Kinase domain in complex with quinoxaline derivatives

PDB Compounds: (A:) Ephrin type-A receptor 3

SCOPe Domain Sequences for d4p5za_:

Sequence, based on SEQRES records:

>d4p5za_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vhefakeldatnisidkvvgagefgevcsgrlklpskkeisvaiktlkvgytekqrrdfl
geasimgqfdhpniirlegvvtkskpvmivteymengsldsflrkhdaqftviqlvgmlr
giasgmkylsdmgyvhrdlaarnilinsnlvckvsdfglsrvleddpeaayttrggkipi
rwtspeaiayrkftsasdvwsygivlwevmsygerpywemsnqdvikavdegyrlpppmd
cpaalyqlmldcwqkdrnnrpkfeqivsildklirnpgslkiitsaaarpsnlll

Sequence, based on observed residues (ATOM records):

>d4p5za_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
vhefakeldatnisidkvvgagefgevcsgrlklpskkeisvaiktlkvgytekqrrdfl
geasimgqfdhpniirlegvvtkskpvmivteymengsldsflrkhdaqftviqlvgmlr
giasgmkylsdmgyvhrdlaarnilinsnlvckvsdfpirwtspeaiayrkftsasdvws
ygivlwevmsygerpywemsnqdvikavdegyrlpppmdcpaalyqlmldcwqkdrnnrp
kfeqivsildklirnpgslkiitnlll

Timeline for d4p5za_:

• d4p5za_ first appeared in SCOPe 2.04
  
• d4p5za_ appears in SCOPe 2.07