SCOPe 2.05: Domain d4muib_: 4mui B:

Lineage for d4muib_ (4mui B:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.26: Adenine nucleotide alpha hydrolase-like [52373] (3 superfamilies)
   core: 3 layers, a/b/a ; parallel beta-sheet of 5 strands, order 32145

4. Superfamily c.26.1: Nucleotidylyl transferase [52374] (6 families)

5. Family c.26.1.4: Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63976] (2 proteins)
   contains C-terminal subdomain similar to one structural repeat of the Creatinase/aminopeptidase family
   automatically mapped to Pfam PF02569

6. Protein Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) [63977] (5 species)

7. Species Mycobacterium tuberculosis [TaxId:1773] [89615] (48 PDB entries)

8. Domain d4muib_: 4mui B: [259221]
   automated match to d1mopb_
   complexed with 2dq, edo, eoh

Details for d4muib_

PDB Entry: 4mui, 2.1 Å

PDB Description: crystal structure of pantothenate synthetase in complex with 2-(5- methoxy-2-(4-methoxyphenylsulfonylcarbamoyl)-1h-indol-1-yl)acetic acid

PDB Compounds: (B:) Pantothenate synthetase

SCOPe Domain Sequences for d4muib_:

Sequence, based on SEQRES records:

>d4muib_ c.26.1.4 (B:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
aipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsv
vvvsifvnpmqfgaggdldayprtpdddlaqlraegveiaftpttaamypdglrttvqpg
plaaeleggprpthfagvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvav
vgvptvreadglamssrnryldpaqraaavalsaaltaaahaatagaqaaldaaravlda
apgvavdylelrdiglgpmplngsgrllvaarlgttrlldniaieig

Sequence, based on observed residues (ATOM records):

>d4muib_ c.26.1.4 (B:) Pantothenate synthetase (Pantoate-beta-alanine ligase, PanC) {Mycobacterium tuberculosis [TaxId: 1773]}
aipafhpgelnvysapgdvadvsralrltgrrvmlvptmgalheghlalvraakrvpgsv
vvvsifvnppdddlaqlraegveiaftpttaamypdglrttvqpgplaaeleggprpthf
agvltvvlkllqivrpdrvffgekdyqqlvlirqlvadfnldvavvgvptvreadglams
srnryldpaqraaavalsaaltaaahaatagaqaaldaaravldaapgvavdylelrdig
lgpmplngsgrllvaarlgttrlldniaieig

Timeline for d4muib_:

• d4muib_ first appeared in SCOPe 2.04
  
• d4muib_ appears in SCOPe 2.06
  
• d4muib_ appears in the current release, SCOPe 2.08