SCOPe 2.08: Domain d3wf6a_: 3wf6 A:

Lineage for d3wf6a_ (3wf6 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d3wf6a_: 3wf6 A: [259055]
   automated match to d4nusa_
   complexed with fz9, zn

Details for d3wf6a_

PDB Entry: 3wf6, 2.03 Å

PDB Description: Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-indol-3-yl)-3,6-dihydropyridin-1(2H)-yl]-1H-pyrazolo[3,4-d]pyrimidine

PDB Compounds: (A:) Ribosomal protein S6 kinase beta-1

SCOPe Domain Sequences for d3wf6a_:

Sequence, based on SEQRES records:

>d3wf6a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivrnakdtahtkaer
nileevkhpfivdliyafqtggklylileylsggelfmqleregifmedtacfylaeism
alghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvthtfcgtieymapei
lmrsghnravdwwslgalmydmltgappftgenrkktidkilkcklnlppyltqeardll
kkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkpllq

Sequence, based on observed residues (ATOM records):

>d3wf6a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkktkaernileevkhpfiv
dliyafqtggklylileylsggelfmqleregifmedtacfylaeismalghlhqkgiiy
rdlkpenimlnhqghvkltdfglckesihdgtvthtfcgtieymapeilmrsghnravdw
wslgalmydmltgappftgenrkktidkilkcklnlppyltqeardllkkllkrnaasrl
gagpgdagevqahpffrhinweellarkveppfkpllq

Timeline for d3wf6a_:

• d3wf6a_ first appeared in SCOPe 2.04
  
• d3wf6a_ appears in SCOPe 2.07