SCOPe 2.08: Domain d4phna_: 4phn A:

Lineage for d4phna_ (4phn A:)

1. Root: SCOPe 2.08

2. Class a: All alpha proteins [46456] (290 folds)

3. Fold a.39: EF Hand-like [47472] (4 superfamilies)
   core: 4 helices; array of 2 hairpins, opened

4. Superfamily a.39.1: EF-hand [47473] (12 families)
   Duplication: consists of two EF-hand units: each is made of two helices connected with calcium-binding loop

5. Family a.39.1.8: Penta-EF-hand proteins [63550] (7 proteins)

6. Protein Calpain small (regulatory) subunit (domain VI) [47552] (3 species)

7. Species Pig (Sus scrofa) [TaxId:9823] [47555] (7 PDB entries)

8. Domain d4phna_: 4phn A: [258980]
   automated match to d1alva_
   complexed with ca

Details for d4phna_

PDB Entry: 4phn, 1.79 Å

PDB Description: the structural basis of differential inhibition of human calpain by indole and phenyl alpha-mercaptoacrylic acids

PDB Compounds: (A:) Calpain small subunit 1

SCOPe Domain Sequences for d4phna_:

Sequence; same for both SEQRES and ATOM records:

>d4phna_ a.39.1.8 (A:) Calpain small (regulatory) subunit (domain VI) {Pig (Sus scrofa) [TaxId: 9823]}
eevrqfrrlfaqlagddmevsatelmnilnkvvtrhpdlktdgfgidtcrsmvavmdsdt
tgklgfeefkylwnnikkwqaiykqfdvdrsgtigsselpgafeaagfhlnehlysmiir
rysdeggnmdfdnfisclvrldamfrafksldkdgtgqiqvniqewlqltmys

Timeline for d4phna_:

• d4phna_ first appeared in SCOPe 2.04
  
• d4phna_ appears in SCOPe 2.07