SCOPe 2.06: Domain d4oqma_: 4oqm A:

Lineage for d4oqma_ (4oqm A:)

1. Root: SCOPe 2.06

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.37: P-loop containing nucleoside triphosphate hydrolases [52539] (1 superfamily)
   3 layers: a/b/a, parallel or mixed beta-sheets of variable sizes

4. Superfamily c.37.1: P-loop containing nucleoside triphosphate hydrolases [52540] (26 families)
   division into families based on beta-sheet topologies

5. Family c.37.1.1: Nucleotide and nucleoside kinases [52541] (21 proteins)
   parallel beta-sheet of 5 strands, order 23145

6. Protein Thymidine kinase [52552] (4 species)
   contains insert all-alpha subdomain, res. 251-322

7. Species Herpes simplex virus type 1, different strains [TaxId:10298] [52553] (33 PDB entries)
   Uniprot P03176 46-375

8. Domain d4oqma_: 4oqm A: [258965]
   automated match to d1p7cb_
   protein/DNA complex; complexed with fdu, so4

Details for d4oqma_

PDB Entry: 4oqm, 2.2 Å

PDB Description: Crystal structure of thymidine kinase from herpes simplex virus type 1 in complex with F-ARA-EdU

PDB Compounds: (A:) Thymidine kinase

SCOPe Domain Sequences for d4oqma_:

Sequence, based on SEQRES records:

>d4oqma_ c.37.1.1 (A:) Thymidine kinase {Herpes simplex virus type 1, different strains [TaxId: 10298]}
kmptllrvyidgphgmgkttttqllvalgsrddivyvpepmtywrvlgasetianiyttq
hrldqgeisagdaavvmtsaqitmgmpyavtdavlaphiggeagsshapppaltlifdrh
piaallcypaarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpg
erldlamlaairrvygllantvrylqcggswredwgqlsgtavppqgaepqsnagprphi
gdtlftlfrapellapngdlynvfawaldvlakrlrsmhvfildydqspagcrdallqlt
sgmvqthvttpgsipticdlartfaremge

Sequence, based on observed residues (ATOM records):

>d4oqma_ c.37.1.1 (A:) Thymidine kinase {Herpes simplex virus type 1, different strains [TaxId: 10298]}
kmptllrvyidgphgmgkttttqllvrddivyvpepmtywrvlgasetianiyttqhrld
qgeisagdaavvmtsaqitmgmpyavtdavlaphiggeapppaltlifdrhpiaallcyp
aarylmgsmtpqavlafvalipptlpgtnivlgalpedrhidrlakrqrpgerldlamla
airrvygllantvrylqcggswredwgqlsgprphigdtlftlfrapellapngdlynvf
awaldvlakrlrsmhvfildydqspagcrdallqltsgmvqthvttpgsipticdlartf
aremge

Timeline for d4oqma_:

• d4oqma_ first appeared in SCOPe 2.04
  
• d4oqma_ appears in SCOPe 2.05
  
• d4oqma_ appears in SCOPe 2.07
  
• d4oqma_ appears in the current release, SCOPe 2.08