SCOPe 2.04: Domain d4k4he3: 4k4h E:386-576

Lineage for d4k4he3 (4k4h E:386-576)

1. Root: SCOPe 2.04

2. Class d: Alpha and beta proteins (a+b) [53931] (380 folds)

3. Fold d.218: Nucleotidyltransferase [81302] (1 superfamily)
   core: alpha-beta-turn-beta-X-beta-(alpha); mixed beta-sheet, order of core strands: 123

4. Superfamily d.218.1: Nucleotidyltransferase [81301] (16 families)

5. Family d.218.1.2: DNA polymerase beta-like [81300] (5 proteins)
   insert X in the core is an alpha-beta(2) unit; mixed 5-stranded sheet, order: 12543; contains extra C-terminal alpha+beta subdomain

6. Protein DNA polymerase lambda [102943] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [102944] (25 PDB entries)

8. Domain d4k4he3: 4k4h E:386-576 [258919]
   Other proteins in same PDB: d4k4he1, d4k4he2
   automated match to d1rzta3
   protein/DNA complex; complexed with 1rz, act, ca

Details for d4k4he3

PDB Entry: 4k4h, 2.1 Å

PDB Description: ternary crystal structures of a human dna polymerase lambda in complex with dna and (-)3tc-tp.

PDB Compounds: (E:) DNA polymerase lambda

SCOPe Domain Sequences for d4k4he3:

Sequence, based on SEQRES records:

>d4k4he3 d.218.1.2 (E:386-576) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdgrshrgifs
rlldslrqegfltddlvsqeengqqqkylgvcrlpgpgrrhrrldiivvpysefacally
ftgsahfnrsmralaktkgmslsehalstavvrnthgckvgpgrvlptptekdvfrllgl
pyrepaerdwl

Sequence, based on observed residues (ATOM records):

>d4k4he3 d.218.1.2 (E:386-576) DNA polymerase lambda {Human (Homo sapiens) [TaxId: 9606]}
rmpreeateieqtvqkaaqafnsgllcvacgsyrrgkatcgdvdvlithpdgrshrgifs
rlldslrqegfltddlvsqegqqqkylgvcrlpgpgrrhrrldiivvpysefacallyft
gsahfnrsmralaktkgmslsehalstavvrnthgckvgpgrvlptptekdvfrllglpy
repaerdwl

Timeline for d4k4he3:

• d4k4he3 is new in SCOPe 2.04-stable
  
• d4k4he3 appears in SCOPe 2.05
  
• d4k4he3 appears in the current release, SCOPe 2.08