SCOPe 2.07: Domain d4cx2a_: 4cx2 A:

Lineage for d4cx2a_ (4cx2 A:)

1. Root: SCOPe 2.07

2. Class d: Alpha and beta proteins (a+b) [53931] (388 folds)

3. Fold d.174: Nitric oxide (NO) synthase oxygenase domain [56511] (1 superfamily)
   unusual fold

4. Superfamily d.174.1: Nitric oxide (NO) synthase oxygenase domain [56512] (1 family)
   automatically mapped to Pfam PF02898

5. Family d.174.1.1: Nitric oxide (NO) synthase oxygenase domain [56513] (2 proteins)

6. Protein automated matches [190421] (6 species)
   not a true protein

7. Species Cow (Bos taurus) [TaxId:9913] [188827] (44 PDB entries)

8. Domain d4cx2a_: 4cx2 A: [258902]
   automated match to d3e7sa_
   complexed with act, h2b, hem, hw1, zn

Details for d4cx2a_

PDB Entry: 4cx2, 2.04 Å

PDB Description: structure of bovine endothelial nitric oxide synthase heme domain in complex with 6-(5-(((3r,4r)-4-((6-amino-4-methylpyridin-2-yl)methyl) pyrrolidin-3-yl)oxy)pentyl)-4-methylpyridin-2-amine

PDB Compounds: (A:) Nitric oxide synthase, endothelial

SCOPe Domain Sequences for d4cx2a_:

Sequence, based on SEQRES records:

>d4cx2a_ d.174.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprkaqtrpspgpppaeqll
sqardfinqyyssikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprc
vgriqwgklqvfdardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriw
nsqlvryagyrqqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfv
lppelvlevplehptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigt
rnlcdphryniledvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaat
vsfmkhldneqkarggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Sequence, based on observed residues (ATOM records):

>d4cx2a_ d.174.1.1 (A:) automated matches {Cow (Bos taurus) [TaxId: 9913]}
gpkfprvknwelgsitydtlcaqsqqdgpctprrclgslvlprpaeqllsqardfinqyy
ssikrsgsqaheerlqeveaevastgtyhlreselvfgakqawrnaprcvgriqwgklqv
fdardcssaqemftyicnhikyatnrgnlrsaitvfpqrapgrgdfriwnsqlvryagyr
qqdgsvrgdpanveitelciqhgwtpgngrfdvlplllqapdeapelfvlppelvlevpl
ehptlewfaalglrwyalpavsnmlleigglefsaapfsgwymsteigtrnlcdphryni
ledvavcmdldtrttsslwkdkaaveinlavlhsfqlakvtivdhhaatvsfmkhldneq
karggcpadwawivppisgsltpvfhqemvnyilspafryqpdpw

Timeline for d4cx2a_:

• d4cx2a_ first appeared in SCOPe 2.04
  
• d4cx2a_ appears in SCOPe 2.06
  
• d4cx2a_ appears in the current release, SCOPe 2.08