Lineage for d3wf5a_ (3wf5 A:)

  1. Root: SCOPe 2.05
  2. 1886641Class d: Alpha and beta proteins (a+b) [53931] (381 folds)
  3. 1929110Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
    consists of two alpha+beta domains, C-terminal domain is mostly alpha helical
  4. 1929111Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families) (S)
    shares functional and structural similarities with the ATP-grasp fold and PIPK
  5. 1932524Family d.144.1.0: automated matches [191359] (1 protein)
    not a true family
  6. 1932525Protein automated matches [190417] (21 species)
    not a true protein
  7. 1932655Species Human (Homo sapiens) [TaxId:9606] [187294] (615 PDB entries)
  8. 1933020Domain d3wf5a_: 3wf5 A: [258876]
    automated match to d4nusa_
    complexed with fz8, zn

Details for d3wf5a_

PDB Entry: 3wf5 (more details), 2.1 Å

PDB Description: Crystal structure of S6K1 kinase domain in complex with a pyrazolopyrimidine derivative 4-[4-(1H-benzimidazol-2-yl)piperidin-1-yl]-1H-pyrazolo[3,4-d]pyrimidine
PDB Compounds: (A:) Ribosomal protein S6 kinase beta-1

SCOPe Domain Sequences for d3wf5a_:

Sequence, based on SEQRES records: (download)

>d3wf5a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkkamivrnakdtahtkaer
nileevkhpfivdliyafqtggklylileylsggelfmqleregifmedtacfylaeism
alghlhqkgiiyrdlkpenimlnhqghvkltdfglckesihdgtvthtfcgtieymapei
lmrsghnravdwwslgalmydmltgappftgenrkktidkilkcklnlppyltqeardll
kkllkrnaasrlgagpgdagevqahpffrhinweellarkveppfkpllq

Sequence, based on observed residues (ATOM records): (download)

>d3wf5a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
kirpecfellrvlgkggygkvfqvrkvtgantgkifamkvlkktkaernileevkhpfiv
dliyafqtggklylileylsggelfmqleregifmedtacfylaeismalghlhqkgiiy
rdlkpenimlnhqghvkltdfglckesihdgtvthtfcgtieymapeilmrsghnravdw
wslgalmydmltgappftgenrkktidkilkcklnlppyltqeardllkkllkrnaasrl
gagpgdagevqahpffrhinweellarkveppfkpllq

SCOPe Domain Coordinates for d3wf5a_:

Click to download the PDB-style file with coordinates for d3wf5a_.
(The format of our PDB-style files is described here.)

Timeline for d3wf5a_: