SCOPe 2.05: Domain d4qj1c_: 4qj1 C:

Lineage for d4qj1c_ (4qj1 C:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.1: TIM beta/alpha-barrel [51350] (33 superfamilies)
   contains parallel beta-sheet barrel, closed; n=8, S=8; strand order 12345678
   the first seven superfamilies have similar phosphate-binding sites

4. Superfamily c.1.5: Inosine monophosphate dehydrogenase (IMPDH) [51412] (2 families)
   The phosphate moiety of substrate binds in the 'common' phosphate-binding site

5. Family c.1.5.0: automated matches [227276] (1 protein)
   not a true family

6. Protein automated matches [227084] (8 species)
   not a true protein

7. Species Cryptosporidium parvum [TaxId:5807] [234914] (4 PDB entries)

8. Domain d4qj1c_: 4qj1 C: [258798]
   automated match to d4my1c_
   complexed with acy, edo, fmt, imp, n09

Details for d4qj1c_

PDB Entry: 4qj1, 2.42 Å

PDB Description: co-crystal structure of the catalytic domain of the inosine monophosphate dehydrogenase from cryptosporidium parvum with inhibitor n109

PDB Compounds: (C:) inosine-5'-monophosphate dehydrogenase

SCOPe Domain Sequences for d4qj1c_:

Sequence, based on SEQRES records:

>d4qj1c_ c.1.5.0 (C:) automated matches {Cryptosporidium parvum [TaxId: 5807]}
amgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehlma
vgmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdviv
ldsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsictt
rivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsilagt
eespgekeligdtvykyyrgmgsvgamksgsgdryfqekrpenkmvpegiegrvkykgem
egvvyqlvgglrscmgylgsasieelwkkssyveittsglreshvhdveivkevmnys

Sequence, based on observed residues (ATOM records):

>d4qj1c_ c.1.5.0 (C:) automated matches {Cryptosporidium parvum [TaxId: 5807]}
amgtknigkgltfedillvpnysevlprevsletkltknvslkiplissamdtvtehlma
vgmarlggigiihknmdmesqvnevlkvknsgglrvgaaigvneierakllveagvdviv
ldsahghslniirtlkeikskmnidvivgnvvteeatkeliengadgikvgigpgsictt
rivagvgvpqitaiekcssvaskfgipiiadggirysgdigkalavgassvmigsilagt
eespgekeligdtvykyyrgmgsvgamksnkmvpegiegrvkykgemegvvyqlvgglrs
cmgylgsasieelwkkssyveittsglreshvhdveivkevmnys

Timeline for d4qj1c_:

• d4qj1c_ first appeared in SCOPe 2.04
  
• d4qj1c_ is called d4qj1c1 in SCOPe 2.06
  
• d4qj1c_ appears in the current release, SCOPe 2.08, called d4qj1c1