SCOPe 2.05: Domain d4qa1c_: 4qa1 C:

Lineage for d4qa1c_ (4qa1 C:)

1. Root: SCOPe 2.05

2. Class c: Alpha and beta proteins (a/b) [51349] (148 folds)

3. Fold c.42: Arginase/deacetylase [52767] (1 superfamily)
   3 layers: a/b/a, parallel beta-sheet of 8 strands, order 21387456

4. Superfamily c.42.1: Arginase/deacetylase [52768] (3 families)

5. Family c.42.1.2: Histone deacetylase, HDAC [52773] (4 proteins)
   automatically mapped to Pfam PF00850

6. Protein automated matches [190786] (1 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [188039] (24 PDB entries)

8. Domain d4qa1c_: 4qa1 C: [258793]
   automated match to d2v5wb_
   complexed with b3n, gol, k, zn

Details for d4qa1c_

PDB Entry: 4qa1, 1.92 Å

PDB Description: Crystal structure of A188T HDAC8 in complex with M344

PDB Compounds: (C:) Histone deacetylase 8

SCOPe Domain Sequences for d4qa1c_:

Sequence, based on SEQRES records:

>d4qa1c_ c.42.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqegdddhpdsieyglgydcpategifdyaaaiggatitaaqclidgmckv
ainwsggwhhakkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedtfsfts
kvmtvslhkfspgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyq
afnpkavvlqlgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantar
cwtyltgvilgktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnl
khv

Sequence, based on observed residues (ATOM records):

>d4qa1c_ c.42.1.2 (C:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
lvpvyiyspeyvsmcdslakipkrasmvhslieayalhkqmrivkpkvasmeematfhtd
aylqhlqkvsqeyglgydcpategifdyaaaiggatitaaqclidgmckvainwsggwhh
akkdeasgfcylndavlgilrlrrkferilyvdldlhhgdgvedtfsftskvmtvslhkf
spgffpgtgdvsdvglgkgryysvnvpiqdgiqdekyyqicesvlkevyqafnpkavvlq
lgadtiagdpmcsfnmtpvgigkclkyilqwqlatlilggggynlantarcwtyltgvil
gktlsseipdhefftaygpdyvleitpscrpdrnephriqqilnyikgnlkhv

Timeline for d4qa1c_:

• d4qa1c_ first appeared in SCOPe 2.04
  
• d4qa1c_ appears in SCOPe 2.06
  
• d4qa1c_ appears in the current release, SCOPe 2.08