SCOPe 2.05: Domain d4q5sc_: 4q5s C:

Lineage for d4q5sc_ (4q5s C:)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.29: beta and beta-prime subunits of DNA dependent RNA-polymerase [64483] (1 superfamily)
   Multidomain subunits of complex domain organization

4. Superfamily e.29.1: beta and beta-prime subunits of DNA dependent RNA-polymerase [64484] (2 families)
   The catalytic site is formed by the association of two double-psi beta-barrel domains, one from each subunit

5. Family e.29.1.1: RNA-polymerase beta [64485] (3 proteins)

6. Protein RNA-polymerase beta [64488] (2 species)

7. Species Thermus thermophilus [TaxId:274] [75609] (8 PDB entries)
   Uniprot Q8RQE9; part of multichain biological unit

8. Domain d4q5sc_: 4q5s C: [258312]
   Other proteins in same PDB: d4q5sd_, d4q5se_, d4q5sf1, d4q5sf2, d4q5sf3
   automated match to d1smyc_
   protein/DNA complex; protein/RNA complex; complexed with atp, mg, zn

Details for d4q5sc_

PDB Entry: 4q5s, 3 Å

PDB Description: Thermus thermophilus RNA polymerase initially transcribing complex containing 6-mer RNA

PDB Compounds: (C:) DNA-directed RNA polymerase subunit beta

SCOPe Domain Sequences for d4q5sc_:

Sequence, based on SEQRES records:

>d4q5sc_ e.29.1.1 (C:) RNA-polymerase beta {Thermus thermophilus [TaxId: 274]}
meikrfgrireviplpplteiqvesyrralqadvppekrenvgiqaafretfpieeedkg
kgglvldfleyrlgeppfpqdecrekdltyqaplyarlqlihkdtglikedevflghipl
mtedgsfiingadrvivsqihrspgvyftpdparpgryiasiiplpkrgpwidlevepng
vvsmkvnkrkfplvlllrvlgydqetlarelgaygelvqglmdesvfamrpeealirlft
llrpgdppkrdkavayvygliadprrydlgeagrykaeeklgirlsgrtlarfedgefkd
evflptlrylfaltagvpghevddidhlgnrrirtvgelmtdqfrvglarlargvrerml
mgsedsltpaklvnsrpleaaireffsrsqlsqfkdetnplsslrhkrrisalgpggltr
eragfdvrdvhrthygricpvetpeganiglitslaayarvdelgfirtpyrrvvggvvt
devvymtateedrytiaqantplegnriaaervvarrkgepvivspeevefmdvspkqvf
svntnlipflehddanralmgsnmqtqavpliraqapvvmtgleervvrdslaalyaeed
gevakvdgnrivvryedgrlveyplrrfyrsnqgtaldqrprvvvgqrvrkgdlladgpa
sengflalgqnvlvaimpfdgynfedaiviseellkrdfytsihieryeieardtklgpe
ritrdiphlseaalrdldeegvvrigaevkpgdilvgrtsfkgeseptpeerllrsifge
kardvkdtslrvppgeggivvrtvrlrrgdpgvelkpgvrevvrvyvaqkrklqvgdkla
nrhgnkgvvakilpvedmphlpdgtpvdvilnplgvpsrmnlgqilethlglagyflgqr
yispifdgakepeikellaqafevyfgkrkgegfgvdkrevevlrraeklglvtpgktpe
eqlkelflqgkvvlydgrtgepiegpivvgqmfimklyhmvedkmharstgpyslitqqp
lggkaqfggqrfgemevwaleaygaahtlqemltlksddiegrnaayeaiikgedvpeps
vpesfrvlvkelqalaldvqtldekdnpvdifeglask

Sequence, based on observed residues (ATOM records):

>d4q5sc_ e.29.1.1 (C:) RNA-polymerase beta {Thermus thermophilus [TaxId: 274]}
meikrfgrireviplpplteiqvesyrralqadvppekrenvgiqaafretfpieelvld
fleyrlgeppfpqdecrekdltyqaplyarlqlihkdtglikedevflghiplmtedgsf
iingadrvivsqihrspgvyftpdparpgryiasiiplpkrgpwidlevepngvvsmkvn
krkfplvlllrvlgydqetlarelgaygelvqglmdesvfamrpeealirlftllrpgdp
pkrdkavayvygliadprrydlgeagrykaeeklgirlsgrtlarfedgefkdevflptl
rylfaltagvpghevddidhlgnrrirtvgelmtdqfrvglarlargvrermlmgsedsl
tpaklvnsrpleaaireffsrsqlsqfkdetnplsslrhkrrisalgpggltreragfdv
rdvhrthygricpvetpeganiglitslaayarvdelgfirtpyrrvvggvvtdevvymt
ateedrytiaqantplegnriaaervvarrkgepvivspeevefmdvspkqvfsvntnli
pflehddanralmgsnmqtqavpliraqapvvmtgleervvrdslaalyaeedgevakvd
gnrivvryedgrlveyplrrfyrsnqgtaldqrprvvvgqrvrkgdlladgpasengfla
lgqnvlvaimpfdgynfedaiviseellkrdfytsihieryeieardtklgperitrdip
hlseaalrdldeegvvrigaevkpgdilvgrtsfkgeseptpeerllrsifgekardvkd
tslrvppgeggivvrtvrlrrgdpgvelkpgvrevvrvyvaqkrklqvgdklanrhgnkg
vvakilpvedmphlpdgtpvdvilnplgvpsrmnlgqilethlglagyflgqryispifd
gakepeikellaqafevyfgkrkgegfgvdkrevevlrraeklglvtpgktpeeqlkelf
lqgkvvlydgrtgepiegpivvgqmfimklyhmvedkmharstgpyslitqqplggkaqf
ggqrfgemevwaleaygaahtlqemltlksddiegrnaayeaiikgedvpepsvpesfrv
lvkelqalaldvqtldekdnpvdifeglask

Timeline for d4q5sc_:

• d4q5sc_ first appeared in SCOPe 2.04
  
• d4q5sc_ appears in SCOPe 2.06
  
• d4q5sc_ appears in the current release, SCOPe 2.08