SCOPe 2.05: Domain d4p5oa1: 4p5o A:416-686

Lineage for d4p5oa1 (4p5o A:416-686)

1. Root: SCOPe 2.05

2. Class e: Multi-domain proteins (alpha and beta) [56572] (68 folds)

3. Fold e.40: Cullin homology domain [75631] (1 superfamily)
   3 domains: (1) 4-helical bundle; (2) alpha+beta; (3) "winged helix"-like

4. Superfamily e.40.1: Cullin homology domain [75632] (1 family)

5. Family e.40.1.1: Cullin homology domain [75633] (2 proteins)

6. Protein Cullin homolog 1, cul-1 [75634] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [75635] (4 PDB entries)
   Uniprot Q13616 17-776

8. Domain d4p5oa1: 4p5o A:416-686 [258092]
   Other proteins in same PDB: d4p5oa2, d4p5ob_, d4p5oc2, d4p5od_, d4p5og_, d4p5oh_, d4p5oi_, d4p5ok_
   automated match to d1ldja3
   complexed with zn

Details for d4p5oa1

PDB Entry: 4p5o, 3.11 Å

PDB Description: structure of an rbx1-ubc12~nedd8-cul1-dcn1 complex: a ring-e3- e2~ubiquitin-like protein-substrate intermediate trapped in action

PDB Compounds: (A:) Cullin-1

SCOPe Domain Sequences for d4p5oa1:

Sequence, based on SEQRES records:

>d4p5oa1 e.40.1.1 (A:416-686) Cullin homolog 1, cul-1 {Human (Homo sapiens) [TaxId: 9606]}
skspeelarycdsllkkssknpeeaeledtlnqvmekfkkiedkdvfqkfyakmlakrlv
hqnsasddaeasmisklkqacgfeytsklqrmfqdigvskdlneqfkkhltnsepldldf
siqvlssgswpfqqsctfalpselersyqrftafyasrhsgrkltwlyqlskgelvtncf
knrytlqastfqmaillqyntedaytvqqltdstqikmdilaqvlqillkskllvleden
anvdevelkpdtliklylgyknkklrvninv

Sequence, based on observed residues (ATOM records):

>d4p5oa1 e.40.1.1 (A:416-686) Cullin homolog 1, cul-1 {Human (Homo sapiens) [TaxId: 9606]}
skspeelarycdsllkkssknpeeaeledtlnqvmekfkkiedkdvfqkfyakmlakrlv
hqnsasddaeasmisklkqacgfeytsklqrmfqdigvskdlneqfkkhltnsepldldf
siqvlssgswpfqqsctfalpselersyqrftafyasrhsgrkltwlyqlskgelvtncf
knrytlqastfqmaillytvqqltdstqikmdilaqvlqillksklpdtlirvninv

Timeline for d4p5oa1:

• d4p5oa1 first appeared in SCOPe 2.04
  
• d4p5oa1 appears in SCOPe 2.06
  
• d4p5oa1 appears in the current release, SCOPe 2.08