SCOPe 2.08: Domain d4ct2a_: 4ct2 A:

Lineage for d4ct2a_ (4ct2 A:)

1. Root: SCOPe 2.08

2. Class d: Alpha and beta proteins (a+b) [53931] (396 folds)

3. Fold d.144: Protein kinase-like (PK-like) [56111] (1 superfamily)
   consists of two alpha+beta domains, C-terminal domain is mostly alpha helical

4. Superfamily d.144.1: Protein kinase-like (PK-like) [56112] (8 families)
   shares functional and structural similarities with the ATP-grasp fold and PIPK

5. Family d.144.1.0: automated matches [191359] (1 protein)
   not a true family

6. Protein automated matches [190417] (37 species)
   not a true protein

7. Species Human (Homo sapiens) [TaxId:9606] [187294] (1476 PDB entries)

8. Domain d4ct2a_: 4ct2 A: [257766]
   automated match to d4aw1a_
   complexed with atp, dtd, na

Details for d4ct2a_

PDB Entry: 4ct2, 1.25 Å

PDB Description: Human PDK1-PKCzeta Kinase Chimera

PDB Compounds: (A:) 3-phosphoinositide-dependent protein kinase 1

SCOPe Domain Sequences for d4ct2a_:

Sequence, based on SEQRES records:

>d4ct2a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rkkrpedfkfgkilgegsfstvvlarelatsreyaikivekrhvhkenkipyvqrekdvm
srldhpffvklyfcfqddeklylglsyakngellkyirkigsfdetctrfytaeivsale
ylhgkgiihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvspell
teksackssdlwalgciiyqlvaglppfragneglifakiikleydfpekffpkardlve
kllvldatkrlgceemegygplkahpffesvtwenlhqqtppklt

Sequence, based on observed residues (ATOM records):

>d4ct2a_ d.144.1.0 (A:) automated matches {Human (Homo sapiens) [TaxId: 9606]}
rkkrpedfkfgkilgegsfstvvlarelatsreyaikivekrhvipyvqrekdvmsrldh
pffvklyfcfqddeklylglsyakngellkyirkigsfdetctrfytaeivsaleylhgk
giihrdlkpenillnedmhiqitdfgtakvlspeskqaransfvgtaqyvspellteksa
ckssdlwalgciiyqlvaglppfragneglifakiikleydfpekffpkardlvekllvl
datkrlgceemegygplkahpffesvtwenlhqqtppklt

Timeline for d4ct2a_:

• d4ct2a_ first appeared in SCOPe 2.04
  
• d4ct2a_ appears in SCOPe 2.07