SCOPe 2.06: Domain d4o9va_: 4o9v A:

Lineage for d4o9va_ (4o9v A:)

1. Root: SCOPe 2.06

2. Class b: All beta proteins [48724] (177 folds)

3. Fold b.47: Trypsin-like serine proteases [50493] (1 superfamily)
   barrel, closed; n=6, S=8; greek-key
   duplication: consists of two domains of the same fold

4. Superfamily b.47.1: Trypsin-like serine proteases [50494] (5 families)

5. Family b.47.1.2: Eukaryotic proteases [50514] (49 proteins)

6. Protein Matriptase MTSP1 [69284] (1 species)

7. Species Human (Homo sapiens) [TaxId:9606] [69285] (19 PDB entries)

8. Domain d4o9va_: 4o9v A: [257242]
   automated match to d1eaxa_
   complexed with nt4

Details for d4o9va_

PDB Entry: 4o9v, 1.9 Å

PDB Description: Crystal structure of matriptase in complex with inhibitor

PDB Compounds: (A:) Suppressor of tumorigenicity 14 protein

SCOPe Domain Sequences for d4o9va_:

Sequence; same for both SEQRES and ATOM records:

>d4o9va_ b.47.1.2 (A:) Matriptase MTSP1 {Human (Homo sapiens) [TaxId: 9606]}
vvggtdadegewpwqvslhalgqghicgaslispnwlvsaahcyiddrgfrysdptqwta
flglhdqsqrsapgvqerrlkriishpffndftfdydiallelekpaeyssmvrpiclpd
ashvfpagkaiwvtgwghtqyggtgalilqkgeirvinqttcenllpqqitprmmcvgfl
sggvdscqgdsggplssveadgrifqagvvswgdgcaqrnkpgvytrlplfrdwikentg
v

Timeline for d4o9va_:

• d4o9va_ first appeared in SCOPe 2.04
  
• d4o9va_ appears in SCOPe 2.05
  
• d4o9va_ appears in SCOPe 2.07
  
• d4o9va_ appears in the current release, SCOPe 2.08